hrp0089p3-p202 | GH & IGFs P3 | ESPE2018

Final Adult Height After Growth Hormone Treatment in Patients with Turner Syndrome

Ahn Jungmin , Suh Junghwan , Kim Hoseong , Kwon Ahreum

This study aimed to evaluate final adult height after recombinant growth hormone (GH) treatment in girls with Turner syndrome (TS) and elucidate the contributing factors to growth response. (Seventy-four patients with Turner syndrome who were treated with GH and reached adult height and 18 patients without treatment were enrolled in this study. To determine final height gain, we assessed the difference between the final height standard deviation score (SDS) and height SDS at t...

hrp0092fc8.6 | Pituitary, Neuroendocrinology and Puberty Session 1 | ESPE2019

Source and Changes in Serum Level of Kisspeptin in Female Rats at Different Developmental Stages

Kwon Ahreum , Kim Ho-seong , Suh Jungwhan , Choi Han-saem , Song Kyungchul , Suh Yongsuk

Introduction: The Kiss1/Kisspeptin/Kiss1r system is essential for puberty onset and reproductive system development, especially in the hypothalamus. Nevertheless, Kiss1 is expressed in other organs. Additionally, serum kisspeptin has been associated with puberty. However, studies on the developmental changes in serum kisspeptin levels and its main source are limited. Therefore, the aim of this study was to evaluate the developmental ...

hrp0095p2-65 | Diabetes and Insulin | ESPE2022

Effect of carbohydrate counting education in Korean patients with type 1 diabetes.

In Lee Hae , Kwon Ahreum , Suh Junghwan , Lee Myeongseob , Song Kyungchul , Wook Chae Hyun , Kim Ho-Seong

Background: The achievement and maintenance of normoglycemia is one of the most important goals to prevent both short and long-term complications in type 1 diabetes mellitus (T1DM). As carbohydrate acts as the primary macronutrient affecting postprandial glycemic response, carbohydrate counting is crucial in adjusting prandial insulin doses to preserve postprandial blood glucose within normal limits. The purpose of this study is to examine the effect for carbo...

hrp0095p1-257 | Diabetes and Insulin | ESPE2022

A novel mutation in INS gene in an infant with neonatal diabetes mellitus: A case report and functional study

Suh Junghwan , Jin Kim Su , In Lee Hae , Lee Myeongseob , Song Kyungchul , Saem Choi Han , Kwon Ahreum , Wook Chae Hyun , Kim Ho-Seong

Neonatal diabetes mellitus (NDM) is a hyperglycemic status usually diagnosed before first 6 months of life, which is caused by monogenic mutations. INS gene mutation is the second most common cause of permanent NDM, causing misfolding of proinsulin and accumulation in the endoplasmic reticulum, leading to apoptosis of the pancreatic beta cells. We report a case of NDM in a 2-month-old girl with a novel heterozygous mutation of the INS gene, and functional studies to confirm th...