hrp0086rfc13.4 | Management of Obesity | ESPE2016

Which Amount of BMI-SDS Reduction is Necessary to Improve Cardiovascular Risk Factors in Overweight and Obese Children?

Reinehr Thomas , Lass Nina , Toschke Christina , Rothermel Juliane , Lanzinger Stefanie , Holl Reinhard

Background: Knowing the changes of cardiovascular risk factors (CRF) in relation to weight loss would be helpful to advise overweight children and their parents and to decide whether drugs should be prescribed in addition to lifestyle intervention.Objective and hypotheses: The aim of the study was to determine the degree of overweight reduction to improve CRFs in overweight children.Method: We studied changes of blood pressure (BP)...

hrp0094p2-116 | Diabetes and insulin | ESPE2021

Sex differences over two decades for glycaemic control, pump use and insulin dose in patients aged 10-20 years with type 1 diabetes

Boettcher Claudia , Tittel Sascha R. , Meissner Thomas , Gohlke Bettina , Stachow Rainer , Dost Axel , Lanzinger Stefanie ,

Background: Therapy in type 1 diabetes has undergone a fundamental change over the last several decades, especially by the use of technical devices. Another change that took place is the growing awareness of sex differences of all kind, e.g. as influencing factors of metabolic control. Our study aimed to evaluate sex differences over two decades with regard to changes in glycaemic control, with regard to trends in insulin pump use and insulin dose. Migration b...

hrp0097rfc6.4 | Pituitary, neuroendocrinology and puberty 1 | ESPE2023

Earlier Occurrence of Puberty and Pubertal Hair Development in Boys and Girls - Insights from the DPV Initiative Data

Reschke Felix , Gohlke Bettina , Lanzinger Stefanie , Boettcher Claudia , Gemulla Gita , Thiele-Schmitz Susanne , Dunstheimer Desiree , van den Boom Louise , Joachim Woelfle , Reinhard Holl

Introduction: Pubertal onset is signaled by thelarche (in girls) and gonadarche (in boys) and indicates the beginning of the hypothalamic-pituitary-gonadal axis activity. Thus, the onset of pubic hair development usually coincides with adrenarche. Girls worldwide are experiencing earlier puberty, but it is uncertain if this trend affects boys, or if it applies to children with type 1 diabetes (T1D).Aim: The aim of this s...