hrp0086p1-p255 | Diabetes P1 | ESPE2016
Can Thi Bich Ngoc
, Vu Chi Dung
, Bui Phuong Thao
, Nguyen Ngoc Khanh
, Docherty Louise
, Edwards Sian
, Mackay Deborah
, Temple Karen
, Ellard Sian
Background: Transient neonatal diabetes mellitus (TNDM) is a rare form of diabetes mellitus that presents within the first 6 months of life with remission in infancy or early childhood. TNDM is mainly caused by anomalies in the imprinted region on chromosome 6q24; however, recently, mutations in the ABCC8 gene, which encodes sulfonylurea receptor 1, have also been implicated in TNDM.Objective and hypotheses: To describe clinical features and lab...