hrp0098p2-101 | Fat, Metabolism and Obesity | ESPE2024
Bischoff Martin
, Beckhaus Julia
, Ahmad Khalil Dalia
, Sabine Frisch
, Koska Benjamin
, Kiewert Cordula
, Kortmann Rolf-Dieter
, Bison Brigitte
, Friedrich Carsten
, L. Müller Hermann
, Timmermann Beate
Background and aims: Craniopharyngiomas (CPs) are rare, non-malignant tumors near the pituitary and hypothalamus. Besides surgery, radiotherapy plays an important role in the treatment strategy. Both tumor-related factors and treatment can cause severe obesity and neuroendocrine disorders. Clinical studies have shown that endocrine deficits can occur at a dose level of 18Gy and risk increases with higher doses. Proton therapy (PT) is increasingly used in order...