hrp0084fc5.6 | Endocrine Oncology/Turner | ESPE2015

Anti-Müllerian Hormone Levels in Patients with Turner Syndrome: Relation to Karyotype, Pubertal Development and GH Therapy

Hamza Rasha , Mira Marwa , Hamed Amira

Background: Gonadal dysgenesis in Turner syndrome (TS) results in pubertal delay or failure and infertility in most patients. However, up to 30% of girls with TS have spontaneous pubertal development and 2–5% have regular menstrual cycles before the onset of premature menopause. Serum anti-Mullerian (AMH) levels reflect the ovarian reserve in females, even in childhood.Objective and hypotheses: To Asses serum AMH levels in patients with TS and its r...

hrp0095p1-461 | Diabetes and Insulin | ESPE2022

Risks and Metabolic Consequences of Ramadan Fasting on Egyptian Adolescents With Type 1 Diabetes Mellitus

Abdelghaffar Shereen , Shaltout Inas , Madani Hanan , Zaid Sara , Mira Marwa

Background: Although Ramadan fasting is one of the five pillars of Islam and is compulsory for all healthy Muslims from puberty onwards, religious exemptions exist for patients with type 1Diabetes. The risks of fasting include: hyperglycemia, hypoglycemia, ketoacidosis, thrombotic episodes, and dehydration. Many adolescents still insist to fast due to religious or social motives.Objectives: To study the risks and metabol...

hrp0092p1-320 | Diabetes and Insulin (2) | ESPE2019

Assessment of Vascular Endothelial Dysfunction Using Brachial Artery Flow Mediated Dilatation and Carotid Intima Media Thickness in Children and Adolescents with Type 1 Diabetes

Abdelghaffar Shereen , Mira Marwa , Hashem Rania , Abdalla Maisa

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with diabetes. Macro- and micro-vascular complications are involved in the pathophysiology of CVD and the increased risk of developing atherosclerosis in this population. A probable association between type 1 diabetes (Type 1 D) and CVD has been attributed to chronic uncontrolled hyperglycemia, inflammation, endothelial dysfunction (ED), and subclinical manifestations of vascular disease. ...

hrp0095p2-156 | GH and IGFs | ESPE2022

Short Term Effects of Growth Hormone in Children and Adolescents with Growth Hormone Deficiency

Tawfik Sameh , Hassan Mona , Attia Mona , Atef Abeer , Mira Marwa , Dowidar Wafaa , Elkhashab Khaled , Diab Wala

Introduction: Children with Growth Hormone deficiency(GHD) should be treated with r-hGH as early as possible after the diagnosis is made. The primary objectives of therapy is to normalize growth during childhood and to achieve final height within their genetic potential.Objectives: To determine impact of GH treatment on short term linear growth in the 1st year of therapy in children with isolated growth hormone deficienc...

hrp0095p2-260 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Analysis of the spectrum of disorders of sex development in Diabetes, Endocrine and Metabolism Pediatric Unit, Cairo University, Egypt

Abdelghaffar Shereen , Sheba Maha , Mira Marwa , Radwan Noha , Nasr Abdelmonem Engy , Ahmed Samah

Background: The incidence of Disorders of sex development (DSD) in Egypt was reported to be 1 in 3,000 live births. Late diagnosis, severe salt wasting with high morbidity and mortality, and inappropriate sex -assignment are challenging problems that constitute medical and social emergencies. Serum Anti Mullerian Hormone (AMH) and Inhibin B levels are possible tools for assessment of Sertoli cell function that can help early diagnosis of patients with suspecte...