hrp0097p1-348 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Clinical course and genetic analysis in patients with childhood-onset congenital combined pituitary hormone deficiency

Ha Lee Yoon , Young Kim Ka , Hye Lee Da , Jee Kim Min , Jeong Lee Yun , Ah Lee Young , Min Ko Jung , Ho Shin Choong

Background: Congenital combined pituitary hormone deficiency (CPHD) has various clinical presentations and can be caused by genetic defects related to pituitary development. We investigated the clinical features and genetic analysis in Korean patients with congenital CPHD.Method: Among 444 patients diagnosed with CPHD between 1994 and 2021 from Seoul National University Children’s Hospital, 43 patients with congeni...