ESPE Abstracts

Introduction: Adrenal insufficiency is relatively rare in childhood and adolescence. Signs and symptoms may be non specific; therefore, the diagnosis may not be suspected early in the course. It may be categorized as primary or secondary and congenital or acquired. Many etiologies have been reported worldwide of which CAH was the commonest etiology in children.Objective and hypotheses: To determine the clinical features and evolution of ...

Introduction: Allgrove syndrome is a rare autosomal recessive disorder involving alacrymia, achalasia, Addison’s disease (3A) and neurological disorders (4A), it results from mutations in the AAAS gene located on chromosome 12q13 which codes for a protein known as ALADIN (ALacryma Achalasia aDrenal Insufficiency Neurologic disorder). Alacrymia is diagnosed by Schirmer’s test, achalasia by esophageal manometry while adrenal insufficiency is confirmed ...

Introduction: The intrauterine growth retardation (IUGR) is defined by weight and/or height below the 10th percentile of reference population curve.Goal: To determine the predictors of small size at the age of 2 yearsMethod: Longitudinal prospective study from 2012 to 2016. We followed the growth in height and weight of children born with IUGR at term up to the age of 2 years.<p class="abstext"...

Background: Growth hormone deficiency (GHD) is defined as a total or partial deficiency in the secretion of growth hormone (GH) by the somatotropic cells of the anterior pituitary. The exact prevalence of this condition is unknown in Algeria. In Europe and USA, it is estimated between 1/4000 and 1/10000. This variation is explained by clinical polymorphism, the limits of pharmacological stimulation tests for GH stimulation, problems in interpreting the diagnos...