hrp0089p3-p155 | Fat, Metabolism and Obesity P3 | ESPE2018

Effect of Three-Month Diet and Physical Activity on Adipokines and Inflammatory Status in Children with Metabolic syndrome

Stroescu Ramona , Marginean Otilia , Bizerea Teofana , Gafencu Mihai , Doros Gabriela

The prevalence of metabolic syndrome (MetS) in young population continues to rise. Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C reactive protein (CRP) play an important role. This study aimed to determine whether these adipokines are significant markers in defining MetS in pediatric population and to assess the effect of hypocaloric diet and physical activity on serum concentrations of adiponectine, leptin, and high sensitivity CRP (hs-CRP).</p...

hrp0086p2-p491 | Fat Metabolism and Obesity P2 | ESPE2016

Anthropometric, Biological and Imagistical Methods For Assessing the Cardiovascular Risk in Obese Children

Stroescu Ramona , Bizerea Teofana , Lesovici Maria , Marazan Monica , Marginean Otilia

Background: Pediatric obesity has increased worldwide over the last decades, being diagnosed at ever-younger ages.Objective and hypotheses: Evaluation of clinical and biological parameters and changes that occur in children with obesity; metabolic syndrome (MetS) identification in the studied groups; identification, evaluation, analysis and correlation of the adipogenic factors with the carotid intima media thickness (CIMT).Method:...

hrp0095p2-121 | Fat, Metabolism and Obesity | ESPE2022

Age-related cardiometabolic risk in children and adolescents

Bizerea-Moga Teofana-Otilia , Loredana Pantea Cristina , Olah Orsolya , Marginean Otilia

Obesity, the silent pandemic of the 21st century, is being observed at increasingly younger ages. Included in the metabolic syndrome (MetS), it creates a favorable environment for the development of other components, such as impaired glucose tolerance (IGT), insulin resistance (IR), dyslipidemia (DysL) and arterial hypertension (HT). The aim of this study was to asses the influence of birth weight for gestational age (BW-GA) and age on the occurence of MetS and its components....

hrp0086p2-p718 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

Endocrine and Metabolic Evaluation of Children with Neurodevelopmental Disability

Brad Giorgiana-Flavia , Marcovici Tamara , Belei Oana , Bizerea Teofana , Mang Niculina , Tamasanu Raluca , Marginean Otilia

Introduction: Neurodevelopmental disability (NDD) is a common problem in children health, occurring in 5–10% of the pediatric population.Aim: To evaluate the endocrine and metabolic complications described in patients with NDD.Material and method: Children with NDD, aged below 9 years old, admitted to 1st Pediatric Clinic of Children Emergency Hospital, Timişoara, România, between January 2014-March 2016 w...

hrp0082p2-d3-399 | Fat Metabolism &amp; Obesity (2) | ESPE2014

Is Small for Gestational Age Status Associated with an Increase Risk of Atherogenesis?

Stroescu Ramona , Micle Ioana , Marazan Monica , Marginean Otilia , Bizerea Teofana , Doros Gabriela

Background: The ‘catch-up growth’ phenomenon in children born small for gestational age (SGA) has been linked to early onset obesity with the subsequent emergence of metabolic syndrome (MetS). The intima media thickness of the common carotid artery (CIMT) is a well-known marker of subclinical atherosclerosis.Objective and hypotheses: To determine the association between being born SGA and CIMT, a measure of atherogenesis and to investigate meta...

hrp0084p3-990 | Gonads | ESPE2015

The Consequences of Polycystic Ovary Syndrome in Adolescent Girls

Brad Giorgiana Flavia , Marcovici Tamara , Belei Oana , Popoiu Calin , Olariu Laura , David Vlad , Marginean Otilia

Background: Polycystic ovary syndrome (PCOS) represents one of the most common complains for adolescent girls to present to endocrinologist. PCOS has the potential to affect the young person both metabolically, physically, psychologically and socially.Objective: To evaluate the metabolic and psychological consequences of PCOS in adolescent girls.Method: Adolescent girls admitted in the Endocrinology Department of Children Emergency...

hrp0097p2-303 | Late Breaking | ESPE2023

The link between birthweight, obesity and insulin resistance

Olah Orsolya , Ilies Cristina , Atamni Samah , Marginean Otilia , Bizerea-Moga Teofana-Otilia

Background: Childhood obesity has emerged as a global pandemic, posing significant health challenges and necessitating urgent action to address its widespread prevalence and associated metabolic consequences. Understanding the link between childhood obesity, being born large for gestational age (LGA), and insulin resistance (IR) in children is crucial for developing targeted interventions and sustainable preventive measures against long-term health risks assoc...

hrp0097p2-304 | Late Breaking | ESPE2023

Metabolic syndrome in overweight and obese children

Ilies Cristina , Olah Orsolya , Fayad Almohamed , Marginean Otilia , Bizerea-Moga Teofana-Otilia

Introduction: Metabolic syndrome (MetS) is a group of conditions that occur simultaneously, involving excess body fat, arterial hypertension, impaired glucose metabolism and dyslipidemia. Establishing effective preventive measures and therapies requires an understanding of the relationship between childhood obesity and the early development of MetS components.Objective: The aim of this study was to identify and explore t...

hrp0092p2-116 | Fat, Metabolism and Obesity | ESPE2019

Nonalcoholic Fatty Liver Disease in Pediatric Obese Patients

Flavia Brad Giorgiana , Corina Tamașanu Raluca , Lațcu Manuela Ioana , Ada Bugi Meda , Marginean Otilia

Background: Nonalcoholic fatty liver disease (NAFLD) represents one of the most important chronic liver diseases and it is an important component of the metabolic syndrome in obese patients. As severity, it includes several clinicopathological entities such as simple steatosis, nonalcoholic fatty liver (NAFL), nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.Aims of study: To evaluate the presence of NAFLD diagnose...

hrp0086p1-p356 | Gonads &amp; DSD P1 | ESPE2016

A New International Registry Highlights the Differences in Practice for Reaching a Diagnosis of CAH – On Behalf of the I-CAH/I-DSD Registry User Group

Kourime Mariam , Bryce Jillian , Jiang Jipu , Karunasena Nayananjani , Guran Tulay , Hannema Sabine Elisabeth , Cools Martine , Van Der Grinten Hedi L Claahsen , Krone Nils , Darendeliler Feyza , Balsamo Antonio , Bonfig Walter , Nordenstrom Anna , Hiort Olaf , Dagmar Lallemand , Ross Richard , Ahmed Syed Faisal , Koehler Birgit , Acerini Carlo , Mendonca Berenice B , Bertelloni Silvano , Lisa Lidka , Bonfig Walter , Elsedfy Heba , Marginean Otilia

Background: Following the 2010 CAH consensus, the need for genetic confirmation of diagnosis remains uncertain and variation in practice is unclear.Methods: This variation was assessed by using the International CAH(I-CAH) Registry which was developed using the same platform as the I-DSD Registry.Results: After the development of the I-CAH Registry in October 2014, the rate of addition of CAH cases increased from 2/month to 14/mont...