hrp0086rfc13.2 | Management of Obesity | ESPE2016

The Use of Proteomics in the Assessment of Health Status of Offspring Born after Intracytoplasmic Sperm Injection (ICSI)

Kosteria Ioanna , Gkourogianni Alexandra , Papadopoulou Aggeliki , Anagnostopoulos Athanasios , Chrousos George , Tsagaris George , Kanaka-Gantenbein Christina

Background: Several studies have correlated Assisted Reproduction Technologies (ART) including classic IVF and Intacytoplasmic Sperm Injection (ICSI) with epigenetic alterations in the offspring that could have long lasting unfavorable metabolic effects. Proteomics, a state-of-the-art technology used for the identification of early biomarkers of disease, has already been implemented in the search of success in ART but not yet for such markers evaluation in offspring of ART.</p...