hrp0097p1-173 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023
Loch Batista Rafael
, Coelho Fernando
, Craveiro Flora
, Dallago Renata
, Domenice Sorahia
, Viana Publio
, Dantas Patricia
, Carvalho Filomena
, Mendonca Berenice
Introduction: Complete Androgen Insensitivity Syndrome (CAIS) is characterized by a complete external genitalia appearance and testicular development in 46,XY individuals harboring pathogenic allelic variants in the AR gene. Due to growing evidence regarding the low risk of germ cell tumors (GCT) in AIS. Prophylactic gonadectomy has been debatable in the CAIS management, mainly due to the absence of an accurate biomarker for GCT....