hrp0097p1-447 | Fat, Metabolism and Obesity | ESPE2023

A comparison of the usefulness of two indices of insulin resistance: IRIHOMA (calculated from fasting glucose and insulin values) and IRIBelfiore (calculated from OGTT results) in diagnosis of metabolic complications and determining indications for possible dietary or pharmacological treatment in children

Łupińska Anna , Kolasa-Kicińska Marzena , Jeziorny Krzysztof , Smalczewska Paula , Rajewska Sylwia , Krasińska Joanna , Stawerska Renata , Lewiński Andrzej

Introduction: The increasing prevalence of obesity in children and adolescents is contributing to the increasing diagnosis of insulin resistance (IR) in these individuals. However, it remains a worldwide problem to establish diagnostic criteria of IR in the developmental-age population. IRIHOMA and the IRIBelfiore are the well-known indices used in clinical practice. The aim of the study was to compare the usefulness of IRIBelfiore and IRIHOMA in the early dia...

hrp0098p1-162 | GH and IGFs 2 | ESPE2024

An attempt to establish cut-off points for GH concentration during the inhibition test based on the analysis of the test results performed in children without gigantism.

Smalczewska Paula , Stawerska Renata , Kolasa-Kicińska Marzena , Jeziorny Krzysztof , Łupińska Anna , Krasińska Joanna , Pakuła Angelika , Rajewska Sylwia , Zygmunt Arkadiusz

Introduction: A condition that causes strong inhibition of growth hormone (GH) secretion is, among others, hyperglycemia; this phenomenon is used in the diagnosis of suspected GH excess by performing a GH inhibition test after oral administration of glucose (OGTT). In a healthy adult, it has been established that the nadir of GH concentration should not exceed 1 ng/ml (0.4 ng/ml in the case of sensitive tests). It is unclear whether the same standards should a...