hrp0092p1-190 | Diabetes and Insulin (1) | ESPE2019

Periodontal Disease Relates to Diabetes Control in Children and Adolescents with Type 1 Diabetes

Ports Emilija , Pena Alexia , Allen Gabrielle , Gue Sam , Couper Jennifer

Background: Obese children with and without Type 2 diabetes have periodontal disease that relates to systemic inflammation. There is limited data on periodontal disease in children with Type 1 diabetes (T1D).Aim: We aimed to assess periodontal disease markers and its determinants in children and adolescents with T1D.Materials and Methods: Cross-sectional study including 73 children...

hrp0089fc12.6 | Diabetes and Insulin 2 | ESPE2018

Persistent Beneficial Effects of Metformin in Children and Adolescents with Type 1 Diabetes: Adelaide Metformin Randomized Controlled Trial Follow Up

Maftei Oana , Couper Jennifer , Anderson Jemma , Ricci Peter , Gent Roger , Giles Lynne , Pena Alexia

Puberty is a critical period for the development and acceleration of vascular complications in Type 1 diabetes (T1D). We have shown that metformin in addition to insulin improves vascular smooth muscle function and HbA1c in T1D children over 12 months (1). We aimed to determine if children with T1D who received metformin in a randomized controlled trial (RCT) [Trial registration ACTRN126110001148976] have a sustained vascular function improvement 3 years after ceasing metformi...

hrp0089rfc8.3 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2018

Pharmacological Treatment of Adolescent Polycystic Ovary Syndrome (PCOS) According to the 2018 International Evidence-Based Guideline for the Assessment and Management of PCOS

Pena Alexia , Witchel Selma , Hoeger Kathy , Oberfield Sharon , Vogiatzi Maria , Misso Marie , Teede Helena

The treatment of Polycystic Ovary Syndrome (PCOS) during adolescence is controversial. The aim of the international evidence-based guideline was to promote accurate diagnosis, optimal consistent care, prevention of complications and to improve patient experience and health outcomes. Extensive international health professional and patient engagement informed the priorities and core outcomes for the guideline. Internationally nominated panels including women with PCOS and a mult...

hrp0089p1-p235 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P1 | ESPE2018

Diagnosis of Adolescent Polycystic Ovary Syndrome (PCOS) According to the 2018 International Evidence-Based Guideline for the Assessment and Management of PCOS

Pena Alexia , Hoeger Kathy , Oberfield Sharon , Wiitchel Selma , Vogiatzi Maria , Misso Marie , Teede Helena

The diagnosis of Polycystic Ovary Syndrome (PCOS) during adolescence is controversial with adult diagnostic features overlapping with normal physiological events that occur during puberty. The aim of international evidence-based guideline was to promote accurate diagnosis, optimal consistent care, prevention of complications and improve patient experience and health outcomes. Extensive international health professional and patient engagement informed the priorities and core ou...

hrp0089p2-p356 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P2 | ESPE2018

Diagnostic Experiences and Concerns in Adolescents with Polycystic Ovary Syndrome

Pena Alexia , Gibson-Helm Melanie , Byrne Stephanie , Cash Sarah , Hull Louise , Teede Helena

Many women with polycystic ovary syndrome (PCOS) have a delayed diagnosis after seeing multiple health care providers for their symptoms impacting on their physical and emotional well-being (1). In adolescent girls, PCOS diagnosis is even more controversial and challenging than in adult women yet there have been no studies in adolescents evaluating diagnostic experience, their knowledge and concerns. We aimed to evaluate diagnostic experience and concerns regarding PCOS in an ...