hrp0086rfc3.8 | Pituitary | ESPE2016

Anthropometric and Endocrine Features in Children and Adolescents with Type 1 Narcolepsy

Ponziani Virginia , Gennari Monia , Pizza Fabio , Balsamo Antonio , Bernardi Filippo , Plazzi Giuseppe

Background: Childhood NT1 has been associated with endocrine disorders like obesity and precocious puberty. These comorbidities may challenge the diagnosis, require tailored treatments and call for a multidisciplinary approach.Objective and hypotheses: To evaluate the impact of type 1 narcolepsy (NT1) on anthropometric and endocrine features in childhood/adolescence, focusing on weight, pubertal development and growth, and their follow up in treated and ...

hrp0094p1-85 | Pituitary A | ESPE2021

Auxological and endocrine aspects in pediatric patients with type 1 Narcolepsy. Results of long-term follow-up in a pediatric endocrinology center

Assirelli Valentina , Casale Sara , Pizza Fabio , Baronio Federico , Donato Giulio Di , Candela Egidio , Balsamo Antonio , Plazzi Giuseppe , Cassio Alessandra ,

Introduction: Type 1 Narcolepsy is a rare pediatric condition characterized by central hypersomnia secondary to hypocretin deficiency. It can also involve the neuroendocrine axis, in particular determining obesity and central precocious puberty (CPP).Objectives: The primary aim of this study is the evaluation of endocrine and auxological aspects at diagnosis and during follow-up in children affected with T1N, in treatmen...