hrp0089p1-p088 | Diabetes & Insulin P1 | ESPE2018

The Shape of the Glucose Curve and Time to Glucose Peak During an Oral Glucose Tolerance Test as Indicators of Beta Cell Function in Obese Adolescents

Sabolić Lavinia La Grasta , Stipančić Gordana , Šepec Marija Požgaj

Introduction: Morphological characteristics of the glucose concentration curve during an oral glucose tolerance test (OGTT) may reflect differences in insulin secretion and sensitivity. Whether the shape of the glucose curve and time to peak glucose concentration can be used as indicators of beta cell function and markers of type 2 diabetes risk in obese adolecents is still uncertain.Aims/hypothesis: The purpose of this cross-sectional study was to asses...

hrp0095fc7.6 | Growth and Syndromes | ESPE2022

The Multifaceted Burden Experienced by Caregivers of Individuals With Bardet-Biedl Syndrome: Findings from the CARE-BBS Study

Forsythe Elizabeth , Mallya Usha M. , Yang Min , Caroline , Lynn Mary , Grea Ali , Po Jeremy , Haqq Andrea M.

Background: Caregivers of patients with Bardet Biedl syndrome (BBS) face substantial burden from highly prevalent features of the disease, namely hyperphagia, or uncontrollable hunger, and obesity. However, the burden experienced by caregivers of individuals with BBS is not well characterized.Methods: A multicountry cross-sectional survey of caregivers of individuals with BBS was conducted to quantify the burden experien...

hrp0086p1-p472 | Fat Metabolism and Obesity P1 | ESPE2016

Risk factors for Atherosclerosis after Anticancer Treatment in Childhood: The Assessment of Lipid Parameters and Indicators of Susceptibility to Atherosclerosis in a Group of Pediatric Patients after Anticancer Treatment

Połubok Joanna , Jasielska Olimpia , Gonera Aleksandra , Kozicka Marta , Sęga-Pondel Dorota , Kazanowska Bernarda , Barg Barg

Introduction: Lipid disorders are a common complication of anticancer therapy. These disorders may be included in both the metabolic syndrome or also may be associated with increased risk of cardiovascular disease. The aim of our study is to evaluate lipid profile in children after anticancer treatment.Materials and methods: Study group consisted of 44 patients (aged 3.25–16 years) with solid tumors, at least one year after cessation of anticancer t...

hrp0092p3-231 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Falsely Elevated Serum Sex Steroid Hormones in a Girl with Premature Adrenarche

Sabolić Lavinia La Grasta , Požgaj Šepec Marija , Zec Ivana , Mandić Dario , Stipančić Gordana

Background: Laboratory evaluation is crucial for accurate assessment of patients with endocrine disorders. When clinical picture is in obvious contradiction with laboratory results, one should suspect and prove analytical interference.Case presentation: a 6.7-year-old girl presented with sexual and axillary hair accompanied by adult-type body odor. She was tall (height SDS 2.6), with no other signs of virilisation and no...