hrp0095p1-467 | Fat, Metabolism and Obesity | ESPE2022

The Level of Inflammatory Markers and their Relationship with Fat Tissue Distribution in Children with Obesity and Type 2 Diabetes

Akalın Ertürk Beyza , Gülbahar Özlem , Kaynak Şahap Seda , Saadet Deveci Bulut Tuba , Çetinkaya Semra , Savaş Erdeve Şenay

Introduction: Chronic inflammation is closely associated with metabolic disorders such as obesity, insulin resistance and Type 2 DM, and is dependent on abnormal cytokine production and activation of inflammatory signaling pathways. Adipose tissue is a metabolically active organ that can be a source of low-grade chronic inflammation in obese individuals. Our aim in this study; to determine whether there are changes in proinflammatory and antiinflammatory cytok...

hrp0095p1-361 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Blue Light Exposure and Exposure Duration Effects on Rats' Puberty Process

Kılınç Uğurlu Aylin , Bideci Aysun , Mürşide Demirel Ayşe , Take Kaplanoğlu Gülnur , Dayanır Duygu , Gülbahar Özlem , Saadet Deveci Bulut Tuba , Döğer Esra , Orhun Çamurdan M.

Introduction: In the last 10 years, blue light (BL) sources such as tablets and phones has increased in every age group. Especially due to the Covid-19 pandemic, screen exposure has also increased in childhood. However, the effects of BL exposure in the puberty process aren’t clear. We aimed to examine the effect of BL exposure and exposure time on pubertyMethods: Immature eighteen 21-day-old female Sprague Dawley ...

hrp0095p2-218 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Evaluation of The Effects of Carob (Ceratonia Siliqua L.) Fruits on the Puberty of Rats

Kılınç Uğurlu Aylin , Bideci Aysun , Anadol Elvan , Süntar İpek , Take Kaplanoğlu Gülnur , Gülbahar Özlem , Şafak Teksin Zeynep , Dayanır Duygu , Saadet Deveci Bulut Tuba , Uluoğlu Canan , Çamurdan M.Orhun

Introduction: Ceratonia siliqua L. (CS) is from the legumes (Fabaceae) family, and different forms such as carob extract and flour are preferred by parents because it is a natural sweetener and a source of vegetable carbohydrates. CS is rich in polyphenols and flavonoids. When we questioned histories of the cases of early puberty and puberty variants who applied to our clinic, we noticed long-term and regular use in some cases. We planned to experimen...