hrp0089p1-p088 | Diabetes & Insulin P1 | ESPE2018

The Shape of the Glucose Curve and Time to Glucose Peak During an Oral Glucose Tolerance Test as Indicators of Beta Cell Function in Obese Adolescents

Sabolić Lavinia La Grasta , Stipančić Gordana , Šepec Marija Požgaj

Introduction: Morphological characteristics of the glucose concentration curve during an oral glucose tolerance test (OGTT) may reflect differences in insulin secretion and sensitivity. Whether the shape of the glucose curve and time to peak glucose concentration can be used as indicators of beta cell function and markers of type 2 diabetes risk in obese adolecents is still uncertain.Aims/hypothesis: The purpose of this cross-sectional study was to asses...

hrp0092p3-231 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Falsely Elevated Serum Sex Steroid Hormones in a Girl with Premature Adrenarche

Sabolić Lavinia La Grasta , Požgaj Šepec Marija , Zec Ivana , Mandić Dario , Stipančić Gordana

Background: Laboratory evaluation is crucial for accurate assessment of patients with endocrine disorders. When clinical picture is in obvious contradiction with laboratory results, one should suspect and prove analytical interference.Case presentation: a 6.7-year-old girl presented with sexual and axillary hair accompanied by adult-type body odor. She was tall (height SDS 2.6), with no other signs of virilisation and no...