hrp0092p1-179 | Diabetes and Insulin (1) | ESPE2019

Longitudinal Metabolic Control After Initiation of Insulin Pump in 5,040 Pediatric Type-1-Diabetes Subjects – Heterogeneous HbA1c Trajectories Over Three Years from the DPV Registry

Prinz Nicole , Schwandt Anke , Becker Marianne , Biester Torben , Hess Melanie , Holder Martin , Karges Beate , Näke Andrea , von Sengbusch Simone , Tauschmann Martin , Holl Reinhard W.

Objectives: Continuous subcutaneous insulin infusion (CSII) has been associated with lower HbA1c. To explore whether CSII initiation leads to HbA1c improvement in each individual with type-1 diabetes and to identify co-variates which might influence change in HbA1c.Methods: 5,040 pediatric type-1-diabetes subjects (δ20 y, 49% boys, median age at diabetes onset [Q1;Q3]: 5.9 [3.5;8.4] years) ...

hrp0098rfc15.4 | Late Breaking | ESPE2024

Autoimmunity in children with type 1 diabetes in association with the COVID_19 pandemic - results from the prospective DPV Registry

Boettcher Claudia , W Holl Reinhard , Nagl Katrin , Karges Beate , Sengbusch Simone , Welters Alena , Warncke Katharina , Flury Monika , Nahdiyati Diyah , von dem Berge Thekla , Kamrath Clemens

Background and aim: Type 1 diabetes mellitus (T1D) is associated with other autoimmune diseases, often with a sex preference. The onset of the COVID-19 pandemic has led to reports on an increasing risk of autoimmune diseases. Our research aimed to investigate (concomitant) autoimmunity in children with T1D manifestation during the COVID-19 pandemic, considering gender and age, compared to pre-pandemic onset.Methods: We a...