hrp0084p3-679 | Bone | ESPE2015

Carpal Spasm in Hypophosphataemic Patient

Lee Sanghyun , Sim Yeji , Kim Heungsik

Background: Phosphate is an essential ion and plays a vital role in many physiological processes. Carpopedal spasm is known as a symptom of hypocalcaemia, or rarely, hypomagnesemia. We present an unusual case of carpal spasm seen in hypophosphataemia.Case presentation: 14 year old boy was admitted with acute onset of both carpal spasm. He had shrimp salad made 2 days ago, and two times of vomiting and large amount of diarrhea was developed before carpope...

hrp0095lb4 | Late Breaking | ESPE2022

The association between glycated albumin and HbA1c in pediatric acute leukemia patients

Yeun Sim Soo , Bae Ahn Moon , Suh Byung-Kyu

Introduction: Traditionally, HbA1c has been used as a preferred glycemic index in diabetes patients. However, as many acute leukemia patients often present with anemia and/or pancytopenia, HbA1c may not accurately represent blood glucose level in this group. Glycated albumin represents the average level of blood glucose in recent 2-3 weeks, independent of red blood cell life. In this study, we aim to evaluate the usefulness of glycated albumin as glycemic moni...

hrp0086p2-p91 | Adrenal P2 | ESPE2016

Corticosteroid-Induced Adrenal Insufficiency in a Child with T Cell Lymphoblastic Lymphoma

Lee Sang Hyun , Son Kyung Lae , Sim Yeji , Kim Heung Sik

Background: Glucocorticoids play a major role in the treatment of lymphoblastic lymphoma. However, supraphysiological glucocorticoid therapy may cause the secondary adrenal insufficiency.Presentation of case: A 11-year-old boy with T cell lymphoblastic lymphoma, treated according to COG A5971 protocol, experienced sudden onset of tremor and general weakness in the first day after tapering 28 days of glucocorticoid therapy. He had a moon face and pigmenta...

hrp0097p1-421 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Bisphosphonate, sirolimus, atenolol treatment in a 4-year old child diagnosed with Gorham-Stout disease

Jin Park Su , Yeun Sim Soo , Suh Byung-Kyu , Bae Ahn Moon

Gorham-Stout disease(GSD), also known as vanishing bone disease is an extremely rare skeletal disorder characterized by idiopathic intraosseous proliferation of lymphatic vascular structures resulting in progressive resorption of bone. Herein, we report a case of a 4-year-old girl with GSD treated with the combination treatment with bisphosphonate, sirolimus, and atenolol. A 4-year-old girl presented with prolonged back pain for 2 weeks. The thoracolumbar spine radiography rev...

hrp0097p1-32 | Diabetes and Insulin | ESPE2023

Continuous Glucose Monitoring: A possible aid to detect hypoglycemia event during insulin challenge tests

Yeun Sim Soo , Jin Park Su , Bae Ahn Moon , Suh Byung-Kyu

Combined pituitary function test is a dynamic function test used to evaluate the anterior pituitary gland in patients suspected with hypopituitarism. The test comprises insulin challenge test where intravenous insulin injection in order to induce symptomatic hypoglycemia (serum blood glucose <40mg/dL). Insufficient increase in growth hormone and cortisol after the stimulation confirms the diagnosis of growth hormone deficiency and/or adrenal function insufficiency. However,...

hrp0098p1-94 | Sex Endocrinology and Gonads 1 | ESPE2024

Comparative analysis of single cell RNA sequencing in Turner syndrome, female Graves’ disease patient, and normal female

Yeun Sim Soo , Jin Park Su , Baek In-Cheol , Kyung Cho Won , Suh Byung-Kyu

Background: Turner Syndrome (TS) is determine by karyotype analysis marked by loss or partial loss of one X chromosome in female. Apart from the distinctive physical traits such as short stature, sexual infantilism, and low-set ears, TS patients are more susceptible to shorter life expectancy as well as various endocrine disease including autoimmune disease. Previous studies have suggested that X chromosome count variation may play a role in genetic expression...

hrp0092lb-16 | Late Breaking Posters | ESPE2019

Associations Between Pituitary Abnormalities and Treatment Response in Children with Growth Hormone Deficiency. First Multicenter Study in Portugal

Diamantino Catarina , Sofia Simões Ana , Borges Catarina , Costa Carla , Pereira Carla , Vieira Paula , Luísa Leite Ana , Cristina Monteiro Ana , Freitas Joana , Martins Sandrina , Teresa Bernardo Maria , Fonseca Marcelo , Mirante Alice

Background/Aims: Magnetic resonance imaging (MRI) is used to investigate the etiology of growth hormone deficiency (GHD). There is a close relationship between structural changes in the pituitary gland and clinical status.We aimed to investigate the relationship between MRI findings and clinical symptoms and treatment response in children with GHD.Methods: The study was conducted in nine Department...

hrp0092p3-315 | Late Breaking Abstracts | ESPE2019

Associations between Pituitary Abnormalities and Treatment Response in Children with Growth Hormone Deficiency. First Multicenter Study in Portugal

Diamantino Catarina , Simões Ana Sofia , Borges Catarina , Costa Carla , Pereira Carla , Vieira Paula , Leite Ana Luísa , Monteiro Ana Cristina , Freitas Joana , Martins Sandrina , Bernardo Maria Teresa , Fonseca Marcelo , Mirante Alice

Background/Aims: Magnetic resonance imaging (MRI) is used to investigate the etiology of growth hormone deficiency (GHD). There is a close relationship between structural changes in the pituitary gland and clinical status.We aimed to investigate the relationship between MRI findings and clinical symptoms and treatment response in children with GHD.Methods: The study was conducted in nine Department...