ESPE Abstracts

Abstract: The SARS-CoV-2 virus uses ACE2 combined with the transmembrane-protease TMPRSS2 to enter and infect thyroid follicular cells. Studies have reported a higher incidence of hyperthyroidism cases during the COVID-19 pandemic compared to pre-pandemic periods. Studies have also been reported cases of thyroid dysfunction early after mass covid vaccinations. However, there are insufficient data to confirm these associations in children.<p class="abstext"...

Introduction: Automated insulin delivery (AID) systems provide an improvement in metabolic control of patients with type 1 diabetes mellitus (DM1). Our center works with 2 systems: (Control-IQ T-slim (A) and Medtronic780G (B)), each one have their own characteristics that could determine the selection of the users. The aimof the study is to evaluate the metabolic control of patients with DM1 after starting AID and evaluate differences between the two treatment...

Introduction: Central precocious puberty (PPC) is defined by the appearance of sexual characters at a chronological age lower than -2.5DS of the average for the reference population. Diagnostic is clinical but the hormonal assessment is essential. Basal gonadotropin values are not enough for the diagnosis. Gonadotropin-releasing hormone (GnRH) stimulation tests evidence the activation of the hypothalamic-pituitary-gonadal axis, however there is controversy abo...

Introduction: There is a close relationship between cardiovascular disease and diet. While cardiometabolic risk has been demonstrated in adolescents with obesity, there is little information on the advanced lipoprotein profile (ALP) in adolescents with anorexia nervosa and low body weight.Objective: To evaluate the metabolomic-nutritional and cardiac profile in three groups of adolescents: 1. anorexia nervosa and low bod...

The diagnosis of early thelarche is common in Pediatric Endocrinology consultations, with many cases lacking an organic cause. It can either spontaneously resolve, remain stable, or progress to precocious puberty. Early exposure to endocrine-disrupting environmental pollutants (EDs) with estrogenic and/or anti-androgenic effects during pregnancy or childhood may affect the timing of thelarche onset and/or puberty in girls. Further research is needed to better understand the in...