ESPE Abstracts

Introduction: HNF1B gene (OMIM*189907) encodes the transcription factor HNF1B, which is expressed early in embryogenesis, controls gene expression and is involved in multiple tissue and organ development. Mutations of HNF1B account for a complex disorder with multisystemic manifestations (Renal Cysts and Diabetes syndrome, OMIM #137920). Congenital urinary tract abnormalities and HNF1B MODY, a rare cause of diabetes mellitus (DM) (≤5% of M...

Introduction: Adolescents with type 1 diabetes mellitus (T1D) may differ from their healthy peers in respect to sexually transmitted diseases (STDs) knowledge and contraceptive use.Objectives: We aimed to explore sexual knowledge and contraceptive use and associated factors in T1D adolescents compared to healthy peers.Methods: Fifty-eight T1D adolescents (mean±SD age 16.3±2.0...

Introduction: Peripheral diabetic neuropathy (PDN), clinical or subclinical, of large-diameter nerve fibers or small-diameter nerve fibers is a common complication of type 1 diabetes mellitus (T1DM).Aims: Early detection of the prevalence of subclinical PDN by assessing the function of small and large nerve fibers in children and adolescents with T1DM.Methods: The study included 53...