hrp0095p2-189 | Growth and Syndromes | ESPE2022

Does she need growth hormone treatment?

Elkina Stanimira , Halvadzhiyan Irina , Petrova Chayka

Growth retardation in children with type 1 diabetes (T1D) is mostly associated with longterm poor metabolic control or combination with other autoimmune diseases. Although rare it could be due to growth hormone deficiency. We present eleven-year-old girl, diagnosed with T1D at age of 2y6mo., on multiple daily injections (MDI) with analogues. She is raised in poor social conditions – low parental education and income, rare follow-up due to difficult access to healthcare p...

hrp0089p1-p085 | Diabetes & Insulin P1 | ESPE2018

T- and B-Lymphocytes Levels in Children with Type 1 Diabetes in Association with Candida Infection

Elkina Stanimira , Blajeva Svetla , Halvadzhiyan Irina , Botzova Venetziya , Petrova Chayka

Although type 1 diabetes (T1D) is most common autoimmune chronic metabolic disease in childhood, data about the role of T-Lymphocytes (T-Ly) and B-Lymphocytes (B-Ly) in children after the diabetes onset are still controversial. The aim of the study was to evaluate the serum levels of T– and B-Ly in children with T1D as a predisposing factor for genital candidiasis (GC).Material: We studied 71 children with T1D at the age of 6 to 18 years, divided in...

hrp0097p2-213 | Adrenals and HPA Axis | ESPE2023

Pseudohypoaldosteronism in congenital anomaly of the kidneys and urinary tract – case presentation

Elkina Stanimira , Bozhanova Venetsiya , Halvadzhiyan Irina , Petrova Chayka

Introduction: Pseudohypoaldosteronism (PHA) is a clinical syndrome characterized by multiorgan or isolated renal tubular resistance to the effects of aldosterone, resulting in hyperkalemia, metabolic acidosis, and normal to high serum aldosterone levels. PHA may be primary (hereditary) or secondary (acquired). Primary forms are subclassified into two: PHA type 1 (salt-wasting) and PHA type 2 (salt-retaining). Secondary forms are typically associated with sever...

hrp0095p2-252 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Premature ovarian failure in two female patients with 47, XXX karyotype

Halvadzhiyan Irina , Mladenov Wilchelm , Elkina Stanimira , Yordanova Nikolinka , Petrova Chaika , Kovacheva Katia , Boyadzhiev Veselin , Iotova Violeta

Introduction: Premature ovarian failure (POF) is defined as a heterogeneous disease leading to amenorrhea and ovarian failure before the age of 40 years. It is found in 1-3% of women of reproductive age, with some negative consequences such as cardiovascular disease, osteoporosis and sexual dysfunction. Triple X syndrome is characterized by POF with primary or secondary amenorrhea, tall stature, large feet. Girls with triple X syndrome show accelerated growth ...

hrp0094p2-312 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Results from the Implementation of a Growth Disorders Related Twinning Programme (Partners4Growth) at tertiary pediatric endocrinology clinics

Elkina Stanimira , Rankova Kameliya , Avdjieva-Tzavella Daniela , Halvadzhiyan Irina , Stefanova Elisaveta , Kaleva Nartzis , Petrova Chayka , Popova Galina , Iotova Violeta ,

It is well known that early diagnosis of growth disorders in children and their timely treatment are important for better outcomes.Objective: To evaluate the results from the implementation of the Partners4Growth Twinning Programme at Bulgarian tertiary pediatric endocrinology clinics. Materials and Methods: Since 2019 Partners4Growth started operation at 6 centers – 3 experienced in growth disorders reference centers and 3 twin cen...