hrp0092p2-249 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

11-Oxygenated Androgens May be Related to the Virilization of Female External Genitalia Due to the Maternal Androgen-Producing Adrenal Tumor

Nagasaki Keisuke , Takase Kaoru , Tani Tomoyuki , Nyuzuki Hiromi , Ogawa Yohei , Numakura Chikahiko , Honma Keiko , Hasegawa Tomonobu

Background: Fetal-derived androgen excess, such as 21-hydroxylase deficiency (21-OHD), is a major cause of 46,XX disorders of sex development (DSD), but there are rarely is due to maternal androgen excess such as that caused by adrenal tumors or luteoma.Recently, in addition to the classical androgen synthesis pathway, the alternative androgen synthesis by backdoor pathway and 11-oxygenated steroids has been reported for virilization of female patients with 21...

hrp0089p3-p095 | Diabetes & Insulin P3 | ESPE2018

The Relationship between Serum Levels of C-Peptide and the Age, BMI, and Insülin Doses in Reply to: Newly Diagnosed Type 1 Diabetic Children

Karaguzel Gulay , Usta Deniz , Tavaci Ayşegul , Taniş Mustafa , Beyhun Ercument

Background and aim: C-peptide is an important indicator of endogenous insulin release. Our aim was to investigate the association of serum C-peptide levels with age, BMI and insulin doses in newly diagnosed type 1 diabetic (DM1) children.Metods: The patients with newly diagnosed DM1 were enrolled the study and classified as DM1A and DM1B. Clinical and laboratory findings of all the patients were recorded. Daily insulin doses, BMI and its z score were cal...