hrp0097p1-303 | GH and IGFs | ESPE2023
Lussu Anna
, Incandela Valeria
, Guzzetti Chiara
, Ibba Anastasia
, Casula Letizia
, Loche Sandro
Background: The diagnosis of GHD in children is based on auxological, biochemical, neuro-radiological, and genetic tests. Biochemical tests include evaluation of stimulated GH secretion and baseline IGF-1 determination. Although IGF-1 is the most reliable indicator of GH action, its value should always be interpreted in conjunction with other clinical and biochemical parameters. Since IGF-1 has good specificity (about 90%), but low sensitivity (about 70%), nor...