hrp0097p1-50 | Fat, Metabolism and Obesity | ESPE2023

The Gut Microbiota Profile of Children with Prader–Willi Syndrome in China

Lu Wei , Yuan Xiaoxiao , Xu Zhenran , Pei Zhou , Luo Feihong

Background: Prader–Willi syndrome (PWS) is a rare genetic disorder associated with hyperphagia, and excessive weight gain. Patients with PWS are at elevated risk of developing morbid obesity and associated life-threatening complications. Although gut microbiota has been suggested to play a role in disease phenotypes, little is known about its composition and how it relates to hyperphagia.Objective: The aim of this ...