hrp0092p1-361 | GH and IGFs (2) | ESPE2019
Zielinska Nataliya
, Skorodok Yulia
, Malievsky Oleg
, Iotova Violeta
, Rosenfeld Ron G.
, Zadik Zvi
, Vander Shelly
, Pastrak Aleksandra
Background: Once-daily growth hormone (GH) therapy is an effective treatment for children with growth hormone deficiency (GHD), but compliance wanes with ongoing treatment. A once -weekly GH, somatrogon (hGH-CTP), is being developed to reduce the treatment burden of daily dosing for children and caregivers and potentially improve compliance and long-term efficacy. The impact of once-weekly somatrogon on long-term safety, local tolerability and immunogenicity w...