hrp0092p1-367 | GH and IGFs (2) | ESPE2019
Elizabeth Melitza
, Donze Stephany
, Pellikaan Karlijn
, van den Berg Sjoerd
, van Doorn Jaap
, Peeters Robin P.
, Hokken-Koelega Anita C.S.
, de Graaff Laura C.G.
Introduction: Recombinant Growth Hormone (GH) has changed the lives of many patients with Prader-Willi Syndrome (PWS). GH treatment has beneficial effects on body composition, physical performance, cognition, psychomotor development, respiratory function and quality of life of patients with PWS. Due to the narrow therapeutic range, GH treatment is subject to strict limits. Clinicians measure serum immunoreactive Insulin-like Growth Factor 1 ('total IGF-I&#...