hrp0098p2-162 | Growth and Syndromes | ESPE2024

Leptin, ghrelin, and nesfatin-1 in children born small for gestational age with catch up growth

Jin Lee Hye , Seon Noh Eu , Young Jin Hye , Lee Yena , Jun Seo Young , Byul Kwon Eun , Rim Jeong Hwal , Suk Shim Young , Jae Kang Min , Tae Hwang Il

Background: Leptin, ghrelin, and nesfatin-1 are peptide hormones which regulates food intake, energy homeostasis and growth hormone synthesis.Objectives: To evaluate the relationship between leptin, ghrelin and nesfatin-1 with catch-up growth (CUG) in children born small for gestational age (SGA).Methods: A total of 67 children were included; 34 children born SGA without CUG, 17 ch...

hrp0098p2-359 | Late Breaking | ESPE2024

High Frequency of Copy Number Variations as Genetic Causes of Failure to Achieve Catch-Up Growth in Small for Gestational Age Children: A Multicenter Study in Korea

Lee Yena , Jae Kang Min , Rim Jeong Hwal , Young Kim Eun , Noh Eu-seon , young Jin Hye , Byul Kwon Eun , Jin Lee Hye , Seo Young-Jun , Young Kim Nan , Hong Sangkyoon , Hong Il-Tae

Background: Small for gestational age (SGA) children are defined by birth weight and/or length at least 2 standard deviations (S.D) below the population mean for gestational age. Up to 90% of these infants experience catch-up growth within the first two years of life; however, 10-15% fail to do so, remaining short at age 2 (SGA-SS). The etiology of failure to achieve catch-up growth remains largely unknown.Methods: This ...