hrp0082p2-d2-551 | Puberty and Neuroendocrinology (1) | ESPE2014

The Effect of Combined GH and GnRH Agonist Treatment for Near-Final Height Improvement in True Precocious Puberty and Early Puberty

Kim Se Young , Kim Eun Young , Yi Kyung Hee

Purpose: The goal of treatment for true precocious puberty (TPP) and early puberty with GnRH agonist (GnRHa) is to prevent loss of genetic potential of target height (TH). And to regress secondary sex characteristics appropriate for patient’s age. But some patient’s growth velocity (GV) after treatment would decline and suggest that final height (FH) was not improved. So, we investigated the effect of combined GH and GnRHa treatment for near-FH (NFH) improvement....

hrp0084p1-18 | Bone | ESPE2015

Response to Vitamin D Replacement is Determined by Body Surface Area in Children with Vitamin D Deficiency

Chung In Hyuk , Kang Yu Sun , Yoo Eun-Gyong

Background: The serum 25-hydroxyvitamin D (25OHD) levels are known to be lower in obese children, probably due to sequestration of vitamin D in the adipose tissue. However, there is no consensus on the dose adjustment for vitamin D supplementation in obese children with vitamin D deficiency (VDD).Aims: To compare the response to vitamin D replacement in normal weight vs overweight children with VDD, and to investigate the determinant for increment of 25O...

hrp0084p2-531 | Puberty | ESPE2015

Regional Brain Volume and Luteinising Hormone in Girls with Idiopathic Central Precocious Puberty

Kim Eun Young , Park Shin Eui , Kim Min Sun

Background: During puberty, gray matter (GM) volume decreases and white matter (WM) volume increases in brain. It has been suggested that pubertal hormones may induce some neuroanatomical changes during puberty. Central precocious puberty (CPP) is caused by premature activation of the hypothalamus-pituitary-gonadal axis in inappropriately early age. However, little is known about the differences of brain structure (especially brain volume) in idiopathic CPP. Also the relation ...

hrp0084p2-544 | Puberty | ESPE2015

Increasing BMI is Associated with Lower Luteinising Hormone Levels in Girls with Central Precocious Puberty at the Early Pubertal Stage

Lee Hae Sang , Kim Eun Young , Hwang Jin Soon

Background: Girls with precocious puberty have high LH levels and bone age was advanced over chronological age by 1 year. Obese children start puberty at an earlier age than non obese children. The mechanisms that cause obese children to grow faster starting from early childhood are not well defined.Objective and hypotheses: We analysed the effects of obesity on luteinising hormone (LH) secretion by using gonadotropin-releasing hormone (GnRH) tests in gi...

hrp0084p3-1165 | Puberty | ESPE2015

One Year Follow-Up of Asymptomatic Precocious Puberty; Clinical and Laboratory Characteristics

Jang Kyung-Mi , Cho Eun-Mi , Ko Cheol-Woo

Background: Children with bone-age advancement without any pubertal sign (asymptomatic precocious puberty, asmyptomatic PP) were reported (CW Ko,et al, at the Annual Meeting of ESPE, 2012 and 2013).Objective and hypotheses: In our follow-up study, some more children with asmyptomatic PP were enrolled additionally. We analysed their clinical and laboratory characteristics at the time of diagnosis, and they were followed-up prospectively t...

hrp0098p2-220 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Association between Attention Deficit Hyperactivity Disorder, Precocious Puberty and Obesity in Korean girls

Byoul Lee Eun , Chung Sochung , Hee Hong Yong

Objective: Obesity has been reported to be associated with both attention deficit hyperactivity disorder (ADHD) and central precocious puberty. The purpose of the current study was to examine the prevalence of ADHD in girls with central precocious puberty and to compare body mass index (BMI) of the girls with ADHD and CPP together and the girls with CPP alone.Method: Girls with central precocious puberty were prospective...

hrp0089p3-p248 | Growth & Syndromes P3 | ESPE2018

Prediction of Response to Growth Hormone Treatment in Korean Girls with Turner Syndrome

Jung Mo Kyung , Kim Se Young , Lee Ji-Eun , Kim Hae Soon , Yu Jeesuk , Yoo Eun-Gyong

Purpose: Growth hormone (GH) treatment has become common practice in Turner syndrome (TS) to improve final adult height. However, there are only a few studies on the analysis of good responders to GH treatment in TS. The aim of this study is to predict the responsiveness to growth hormone therapy in Turner syndrome.Methods: Among 197 TS patients registered in LG Growth study, 92 patients were excluded because of systemic illness or hypothyroidism. The cl...

hrp0089p2-p392 | Thyroid P2 | ESPE2018

Clinical Characteristics and Predictive Factors for the Detection of Thyroid Cancer in Children with Thyroid Nodules

Suh Junghwan , Choi Han Saem , Kwon Ah Reum , Chae Hyun Wook , Kim Duk Hee , Kim Ho-Seong

Thyroid nodules in children are less common than adults. However, pediatric thyroid nodules have higher rate of malignancy compared with adults, and also have increased risk of metastasis and recurrence. In this study, we analyzed clinical features, laboratory findings, and thyroid ultrasound (US) of children with thyroid nodules to determine predictive factors of thyroid cancer. Total 268 patients under 18 years of age with thyroid nodule whom visited Severance Children’...

hrp0097p1-120 | Growth and Syndromes | ESPE2023

Personalized behavioral change technique intervention with TUITEK® patient support program to support caregivers of children treated with growth hormone in Korea

Wook Chae Hyun , Sil Oh Eun , van Dommelen Paula , Jang Kyungmi , Kyung Jung Mo , Hyang Cho Ja , Suh Junghwan , Eun Moon Jung , Koledova Ekaterina , Yang Yoo-Jin , Yoo Eun-Gyong

Background: Growth hormone (GH) treatment requires long-term self-management and optimized recombinant-human growth hormone (r-hGH) prescription. Patient support programs (PSPs) are vital in educating, providing personalised support to caregivers and enhancing patient care to achieve optimal growth outcomes. Nurse-led PSP calls using behavior change techniques (BCTs) and motivational interviewing principles have demonstrated a meaningful behavior change across...

hrp0095p1-386 | Thyroid | ESPE2022

Relationships of urinary bisphenol A in childhood on thyroid hormone function in adolescents

Eun Choi Jung , Jeong Choi Eun , Lee Seonhwa , Park Bohyun , Ah Lee Hye , Sun Hong Young , Ha Eunhee , Soon Kim Hae , Park Hyesook

Purpose: Bisphenol A (BPA) is endocrine disrupting chemicals used to manufacture plastics such as epoxy resins and polycarbonate polymers. BPA has weak estrogenic and strong anti-androgenic effects and has also been linked to disruption of thyroid function in previous studies. This study aims to investigate the relationship between urinary bisphenol A exposure in early childhood and thyroid hormone of pubertal children in Korea.M...