ESPE Abstracts

Patient satisfaction is of increasing importance and is widely recognized as an indicator of quality of medical care. The aim was to assess children with type 1 diabetes and their families Satisfaction with Healthcare Services.Methods: The study was conducted at Pediatric outpatient clinic, Suez Canal University Hospital, Ismailia Egypt. Eighty children diagnosed with type 1 diabetes for at least 1 year. They were interviewed to obtain t...

A 6 year and 11 month -old girl of a Consanguineous parent. Her family history : has 2 sibling deaths in the neonatal period. her perinatal history :C/S, full term, NICU admission on the 5th day of birth due to vomiting and had generalized hyperpigmentation (external genitalia and skin with No atypical genitalia, her labs revealed hypoglycemia, hyponatremia and hyperkalemia, and her hormonal profile revealed sky high ACTH 2745 pg/ml (N.7.2-63.3 pg/ml), low cortisol 2 ug/dl (N....

Background: Chronic kidney disease (CKD) was defined by structural or functional renal abnormalities, or an estimated glomerular filtration rate (GFR) of less than 60 mL/min per 1.73 m2. A child with CKD may develop many complications such as: anemia, poor growth and nutrition, bone and mineral disorders, cardiovascular complications, and complications of hemodialysis, and peritoneal dialysis.Aim: Assessment of severity ...

Background: Electrophysiological techniques allowed identification of sub-clinical pathological changes and early diagnosis of diabetic peripheral neuropathy (PN). Neopterin is a marker of inflammation and cellular immune response that is elevated in conditions of T-cell or macrophages activation. Diabetic peripheral neuropathy (PN) is associated with inflammatory/immune processes and therefore, we hypothesized that neopterin could be used as a marker of neuropathy in type 1 d...

The “Hybrid Diabetes (HD)” is a new term that emerged in the last few years to describe diabetes with combined features of type 1 and type 2 diabetes. The etiology behind hybrid diabetes is not well understood, and clinical characteristics for these unique patients were not described before. Differentiating HD from other forms of diabetes will lead to a better understanding of the disease process and course, as well as knowing the most appropriate management plan to ...

Introduction: The complicated surgical reconstruction of verilized female patients with congenital adrenal hyperplasia (CAH) aims to achieve normal external genital appearance and to maintain normal urogenital and sexual functions.Objective: To study the urological complications including urinary incontinence, urinary tract infection (UTI) and voiding dysfunction besides assessment of cosmetic outcome after surgical corr...

This comprehensive literature review identified studies reporting MRI findings related to pituitary volume in children with GHD. Studies were selected for their relevance to clinical correlations involving short stature, GH peak levels, IGF-1 levels, and therapy response.Results: The 30 studies reviewed highlight significant structural abnormalities in the pituitary gland of children GHD. Key findings include anterior pituitary hypoplasi...

Background and aims: The impact of GnRH treatment on the timing of menarche, menstrual cycle status, and onset of menopause in girls with early/precocious puberty is of clinical interest. This study aims to provide insight into the effects of GnRH treatment on these aspects.Methods: A comprehensive literature search was conducted on PubMed for English articles published between 2010 and 2023. The focus was on studies, me...

Introduction: This review aims to chronologically summarize MRI findings in children with GHD, correlating these changes with clinical characteristics and GH testing results, and IGF-1 levels.Methods: We reviewed MRI studies conducted from 1991 to 2024, focusing on structural and functional brain changes in children with GHD. Data were extracted from various studies and arranged chronologically.<st...

This review summarizes the prevalence and degree of functional brain changes detected by fMRI in Growth Hormone Deficiency (GHD) patients and their clinical associations in studies from 2019 to 2024Results: Author Year Prevalence of F...