ESPE Abstracts

Background: The Scottish Paediatric Endocrine Managed Clinical Network is committed to providing equity of care and education across Scotland. A key role is the education of health care professionals and how this is delivered. An extensive survey using a Learning Needs Analysis Tool was completed to ascertain learning needs and their delivery across Scotland. This highlighted the desire to have online learning available to health professionals.Objective:...

Key words: hot nodule, pediatrics, papillary thyroid carcinoma A nodule over 1 centimeter observed in pediatrics need further evaluation. Not having ultrasound changes during monitoring does not mean being benign. Moreover, normal FNA does not rule out a malignancy and it is necessary to repeat the test every 3-6 months. The case was a 15-year-old girl with a 23 mm fixed nodule on ultrasound and normal FNA. She developed hyperthyroidism after two years; a hot ...

Context: Physiological growth hormone is secreted during the slow-wave sleep. Traditionally, growth hormone (GH) therapy is given in daily GH injections before sleep. This schedule better imitates the physiological diurnal variation of GH secretion and action. Late-night daily injections have been claimed to be associated with sleep disturbances and insomnia, yet there is no hard evidence supporting this contention. Morning and evening GH injections produce co...

Introduction: Because of the associations and links between abnormal placental weight and both fetal and maternal disorders, it is important to have the national normal standard for placental weight as a normality reference.Aims: To find out the national placental weight standards for babies born between 37th and 43rd weeks of gestation in all groups of males and females babies born AGA, SGA, and LGA.<p class="abstex...

Background: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder associated with isolated glucocorticoid deficiency. Melanocortin−2 receptor (MC2R), account for approximately 25% of FGD cases.Case report: 3 year old girl presented with recurrent hypoglycaemic episodes from day 2 of life. She was a product of consanguineous family born with a birth weight of 2.3 kg. At birth she was found to be dark in complexion from birt...

Background: Abnormal cardiac development leading to CHD can be associated with abnormal placental development with abnormal trophoblast invasion and remodeling resulting in abnormal transfer of nutrients and oxygen.Objective and hypotheses: We measured the anthropometric parameters (length, weight, and head circumference) and the placental weight of 49 FT newborns (gestation period >36 weeks) infants with CHD ((cyanotic (n=8) and acyanotic (...

Introduction: Testicular adrenal rest tumour (TART) is a complication in males with congenital adrenal hyperplasia (CAH). However, the prevalence, risk factors and treatment in children are not clear.Objective: 1) To identify the incidence of TART and risk factors in patients with classical CAH in our centre 2) To study the clinical characteristics, hormonal profile, treatment interventions and outcome of patients with T...

Adrenocortical carcinoma is very rare in children, with annual incidence of 0.21 case per million patient younger than 20 years. At this article I reported two patients. First case was A 16-month-old girl presented with 3 months history of increased appetite and rapid weight gaining, appearance of hair at pubic area for 2 months and acne on face for one-month duration. Parents are non-consanguineous, had no endocrine disorders or tumors. On examination: chubby baby, cushingoid...

Introduction: Monogenic diabetes has been estimated to be 1 - 6% of all diabetic cases in European countries which are primarily non consanguineous populations, while the incidence in highly consanguineous areas is insufficiently defined. However, the genetic aetiology of monogenic diabetes has been shown to be widely different in areas with prevalent consanguinity compared to areas with lower rates. In this single-centre study, we aimed to evaluate the preval...

Introduction: Primary adrenal insufficiency (PAI) is a potentially life-threatening condition that requires appropriate diagnosis and treatment. The most common cause of PAI is congenital adrenal hyperplasia (CAH), but other well-established aetiologies include metabolic and autoimmune disorders, and physical damage. Mutations in more than 30 genes have now been associated with PAI, with considerable biochemical and phenotypic overlap. It is therefore importan...