ESPE Abstracts (2015) 84 P-3-840

Fat

Are Age and Initial BMI-SDS in Obese Children and Adolescents Associated with the BMI-SDS Courses During and after the Attendance of an Inpatient Weight-Loss Program (LOGIC-Trial)?

Stephanie Brandta, Martin Wabitscha, Melanie Heitkampb, Barbara Geilhofb, Helmut Langhofc, Martin Halled & Monika Siegriste

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aDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany; bDepartment of Prevention, Rehabilitation and Sports Medicine, Technische Universität München, Klinikum rechts der Isar, Munich, Germany; cRehabilitation Clinic, Klinik Schönsicht, Berchtesgaden, Germany; dDepartment of Prevention, Rehabilitation and Sports Medicine, Technische Universität München, Klinikum rechts der Isar; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alli, Munich, Germany; eDepartment of Prevention, Rehabilitation and Sports Medicine, Technische Universität München, Klinikum rechts der Isar, Munich, Germany


Background: It has been discussed in literature, that being severely obese and adolescent are predictive for failure in a behavior based weight-loss program.

Objective: To investigate the association between age and initial BMI-SDS with BMI-SDS courses during and after the attendance of an inpatient weight-loss program.

Design: The LOGIC-trial involves overweight and obese children and adolescents (6–19 years), who participate in an inpatient weight-loss program for 4–6 weeks. Height and weight values were taken at the start (T0), at the end of the intervention (T1) and one year after start of the intervention (T2). The study sample includes n=1.046 participants (T0). The recall rate at T2 was relatively high (54.6% of the original cohort). Missing BMI values were replaced by baseline observation carried forward method. Age at baseline (years) was grouped: 7–11 (n=214); 12–14 (n=501); ≧15 (n=331). BMI-SDS values at baseline were grouped by using the 75th internal percentile (low vs. high). Linear mixed effects model (piecewise linear function with a knot at T1) was calculated.

Results: BMI-SDS courses are significantly determined by age and BMI-SDS at baseline. Older children (≧15 yrs) improved the least in reducing BMI-SDS under short-term intervention compared to the younger participants (independent of BMI-SDS at baseline). During 1-year follow-up BMI-SDS increased in all participants. The strongest increase was observed in 12–14 year-old children with a high BMI-SDS at baseline. 12–14 years old children showed the smallest BMI-SDS reduction during FU compared to the younger and older age groups, independent of BMI-SDS at baseline. The BMI-SDS difference (T0–T2) was −0.15 in children (12–14 years) with a low BMI-SDS and −0.05 in children with a high BMI-SDS at baseline.

Conclusion: Age and BMI-SDS at baseline determine the BMI-SDS courses during and after the attendance of an inpatient weight-loss program. The long-term success of an inpatient weight-loss program was lowest in 12–14 years old children.

Funding: The LOGIC-study is funded by the non-profit organization Else Kröner-Fresenius-Stiftung, Bad Homburg, Germany and the German statutory pension insurance scheme, Landshut, Germany.

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