ESPE Abstracts (2015) 84 P-3-1116

ESPE2015 Poster Category 3 Pituitary (31 abstracts)

Hormone Disorder and Vitamin Deficiency in Attention Deficit Hyperactivity Disorder (adhd) and Autism Spectrum Disorders (ASD)

Murat Doğan a , Keziban Aslı Bala a , Tuba Mutluer b , Sultan Kaba a , Oktay Aslan a & Şekibe Zehra Doğan a

aSchool of Medicine, Yuzuncu Yil University, Pediatrics, Van, Turkey; bVan Regional Training and Research Hospital, Pediatric Psychiatry D, Van, Turkey

Objective: To evaluate thyroid hormones and antibodies, vitamins B12 and D levels, ferritin levels, adrenal and gonadal steroid levels in children diagnosed with ADHD and ASD.

Material method: Patients between the ages of 2–18 years followed-up with the diagnosis of ADHD and ASD in the Van region were included in this study. The weights and heights of the patients were recorded and then the blood samples were obtained between 0800 and 0900 h. in the morning due to the diurnal variation of the hormone. 27 cases compatible with the patient group in terms of age and gender and who did not have the diagnostic criteria of ADHD and ASD were taken as the control group.

Findings: While there was no significant difference between the groups for thyroid hormone levels statistically, there was a significant difference in terms of vitamins B12 and D and ferritin statistically. While the highest ferritin and lowest vitamin M12 and vitamin D levels were found in the ASD group, the vitamin D level in the ADHD group was significantly lower than that of the controls, too. There was no statistically significant difference between the groups in terms of adrenal and gonadal hormone levels.

Conclusion: Our study is unique in the literature in terms of including and evaluating ADHD and ASD and the risk factors vitamin B12, ferritin, vitamin D, adrenal androgens, celiac disease and subclinical hypothyroidism. Besides, with the current study, we want to screen the levels and importance of supplementation of vitamin B12 and D in ASD and ADHD group patients and to especially emphasize the informing of the population about vitamin B12 and D deficiency in terms of prevention of these diseases and necessity of stimulation of the health workers in order to take the measures such as diet relieving the deficiency and supplementation.

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