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59th Annual ESPE (ESPE 2021 Online)

22 Sep 2021 - 26 Sep 2021

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The 59th ESPE Annual Meeting will now be held online in September 2021.

ePoster Category 1

Diabetes A

hrp0094p1-21 | Diabetes A | ESPE2021

Incidence of Type 1 Diabetes in Children and Adolescents during the Covid-19 Pandemic in Germany: Results from the DPV registry

Kamrath Clemens , Rosenbauer Joachim , Eckert Alexander , Siedler Kai , Bartelt Heike , Klose Daniela , Sindichakis Marina , Herrlinger Silke , Lahn Valentina , Holl Reinhard W. ,

Objective: The aim of this study was to investigate the incidence of type 1 diabetes in children and adolescents during the Covid-19 pandemic in Germany compared to previous years.Research Design and Methods: Based on data from the multicenter German Diabetes Prospective Follow-up Registry (DPV), we analyzed the incidence of type 1 diabetes per 100,000 patient years in children and adolescents in the year 2020. Using Poisson regression m...

hrp0094p1-22 | Diabetes A | ESPE2021

Early meal reporting enhances post-prandial glycaemic balance but remains underused in teenagers with artificial pancreas

Villeneuve Emma , Lachal Sylvain , Charpentier Guillaume , Franc Sylvia , Tourki Yousra ,

Background and aims: In an artificial pancreas, the meal management depends on the meal size and time being reported to the system. Because of the delay of insulin action, it is recommended to declare a meal in advance to allow insulin to limit the glycaemic peak. We aim to assess if the post-prandial glycaemic balance improves as meals are reported in advance.Clinical dataset: As part of Diabeloop DBLUS clinical trial (NCT04190277), 37 ...

hrp0094p1-23 | Diabetes A | ESPE2021

Capillary blood sample collection at home for HbA1c measurements during the COVID-19 pandemic in children with diabetes mellitus

Qian Hui Lim Rachel , Gireesh Bhat Nikita , Begum Rojina , Shah Pratik Hasmukh , Ayling Ruth , Gevers Evelien ,

Background: The COVID-19 pandemic has resulted in rapid implementation of tele-clinics; patients have frequently missed routine point-of-care HbA1c testing, vital for evaluating long-term glycaemic control. We evaluated the feasibility of remote HbA1c monitoring via self-collection of capillary blood samples at home, and examined clinical characteristics associated with engagement with this system.Methods: Bio-Rad Haemog...

hrp0094p1-24 | Diabetes A | ESPE2021

Resolution of feeding problems in patients with congenital hyperinsulinism

Worth Chris , Hall Caroline , Wilson Sarah , Gilligan Niamh , O’Shea Elaine , Salomon-Estebanez Maria , Dunne Mark , Banerjee Indraneel ,

Background: Congenital Hyperinsulinism (CHI) is the most common cause of recurrent and severe hypoglycaemia in childhood and can be broadly categorised into two subtypes. Diffuse CHI (CHI-D) involving all pancreatic cells is usually treated with medications and rarely subtotal pancreatectomy. Focal CHI (CHI-F) involves a solitary insulin hypersecreting pancreatic lesion and can be cured following surgical lesionectomy. Many patients with CHI-F and CHI-D underg...

hrp0094p1-25 | Diabetes A | ESPE2021

Longitudinal Auxological Recovery and Reduced Neurodevelopmental Problems in Hyperinsulinaemic Hypoglycaemia

Worth Chris , Hashmi Laila Al , Yau Daphne , Salomon-Estebanez Maria , Perez-Ruiz Diego , Hall Caroline , O’Shea Elaine , Pimlott Helen , Foster Peter , Flanagan Sarah , Cosgrove Karen , Dunne Mark , Banerjee Indraneel ,

Background: Hypoglycaemia due to congenital hyperinsulinism (CHI) is the commonest cause of severe, recurrent hypoglycaemia in childhood. Previous follow up studies have focused on neurodevelopmental status which is noted to be delayed in as many as 48% of cases. There has been less emphasis on other long-term outcomes in patients with CHI. Given the requirement for high volume carbohydrate in most patients, there are concerns regarding the adverse effects on ...

hrp0094p1-26 | Diabetes A | ESPE2021

Efficacy and Tolerability of GLP-1 Receptor Agonists in Children and Adolescents with Obesity

Ryan Paul ,

Background: Rates of pediatric obesity are on a concerning upward trajectory globally, with the prevalence approaching 1 in 5 children and adolescents aged 2-19 years in the United States. As a direct consequence of this obesity surge, we will continue to experience a substantial adult cardiometabolic burden. Although public health measures to optimize lifestyle interventions and reduce culpable environmental exposures are the primary target for governments an...

hrp0094p1-27 | Diabetes A | ESPE2021

The SARS-CoV-2 Pandemic Is Associated With Increased Severity Of Presentation Of Childhood Onset Type 1 Diabetes Mellitus: A Multicentre Study Of The First COVID-19 Wave

McGlacken-Byrne Sinead M , Drew Samantha EV , Turner Kelly , Peters Catherine , Amin Rakesh ,

Objective: Children are usually mildly affected by Severe Acute Respiratory Syndrome Coronavirus 2 infection (SARS-CoV-2, COVID-19). However, the pandemic has impacted negatively on children with non-COVID-19 diseases. We aimed to determine the impact of the COVID-19 pandemic on the presentation of newly diagnosed childhood-onset type 1 diabetes.Methods: This was a cross-sectional study conducted over a one-year period. ...

hrp0094p1-28 | Diabetes A | ESPE2021

Glycemic control and changes in habits in patients with type 1 diabetes during the lockdown due to the COVID-19 pandemic

Valls Aina , Murillo Marta ,

Background: The SARS-CoV-2 pandemic has forced the authorities to impose a lockdown to minimize the risk of infection. This extreme and prolonged situation has caused changes in habits, dietary and glycemic control in children with type 1 diabetes (T1D). Continuous glucose monitoring (CGM) and Flash glucose monitoring (FGM) have allowed health care professionals to a remote control of the patients.Aim: The aim of the stu...

hrp0094p1-29 | Diabetes A | ESPE2021

Incidence and severity of new-onset paediatric Type 1 diabetes in the COVID-19 pandemic – a UK multicentre perspective

Ponmani Caroline , Sakka Sophia , Wickramarachchi Chandu , Redpath Yvette , Ajzensztejn Michal , Kanumakala Shankar , Hulse Tony ,

Background: Paediatric diabetes has been the focus of attention during the COVID-19 pandemic. There are reports of increased incidence of new-onset type 1 paediatric diabetes and concerns about delayed presentations to the Emergency Department (ED) due to parental fears of SARS-CoV-2, resulting in an increase in the incidence and severity of DKA in children with new-onset diabetes.Objectives: To characterise the features...

hrp0094p1-30 | Diabetes A | ESPE2021

Metabolic Control and Health-Related Quality of Life in Children with Diabetes Mellitus during the COVID-19 Pandemic: Results from a Prospective Swiss Cohort Study

Vural Serpil , Kahlert Christian , Gozzi Tiziana , Heldt Katrin , Roduit Caroline , Lauener Roger , l’Allemand Dagmar ,

Introduction: The COVID-19 pandemic led to regional lockdowns and restrictions associated with changes in lifestyle and quality of life (QoL) thus potentially burdening metabolic control in Diabetes Mellitus (DM). We examined whether the stages of restrictions lead to changes in QoL and metabolic control in children with DM.Methods: Starting in April 2020, this monocentric prospective longitudinal cohort study included c...