ESPE2022 Poster Category 2 Growth and Syndromes (44 abstracts)
Growth of extremely low birth weight infants (ELBW) at a tertiary hospital: catch-up growth continues during the 3rd year of life.
Fawzia Alyafei , Ashraf Soliman , Fatima Alkhori , Saleha Abbasi , Hamdy Ali , Nada Alaaraj , Noor Hamed , Shayma Ahmed & Noora Alhemaidi
Hamad General Hospital, Doha, Qatar
Introduction: An extremely low birth weight (ELBW) infant is defined as one with a birth weight of less than 1000 g. This study evaluated the postnatal growth of infants born with ELBW for 3 years.
Method: Anthropometric measures (z scores) from birth, 2,4.6,12,18,24, and 36 months were measured in 87 randomly selected infants who were born with a birth weight below 1 kg (between 9-2016 and 9-2018). Their anthropometric data were compared to standard growth for normal age and sex using WHO growth standards without correction for gestational age. All preterm babies received preterm formula for an average of 4-6 months.
Results: Their gestational age (GA) at delivery ranged between 23 and 27.5 weeks. They had weight z score (mean +/- SE) (WAZ) = -7.7 +/-0.14, length Z score (LAZ) = -8.8 +/-0.25 and weight for length Z score (WLZ) =-5.6 +/-0.39 and head circumference z score (HCZ) = -8.8 +/-0.3. ELBW infants had a progressive gain in WAZ for the first 24 months (from -7.7 to -0.52). The catch-up in WAZ stopped during the third year of life. They had a progressive increase in LAZ for 3 years (from -8.8 to -0.34). The catch-up in LAZ continued considerably during the third year of life. Their WLZ increased significantly during the first year (from -5.6 to -0.1) with maximum gain during the first 6 months of life. This can be explained by a faster gain in weight compared to the gain in length during this period. They had a mild decrease in WLZ during the next two years. This is due to a relatively faster gain in LAZ compared to WAZ.
| 0.00 | 2 mon | 4 mon | 6 mon | 12 mon | 18 mon | 24 mon | 36 mon | ||
| WAZ | mean | -7.72 | -7.69 | -4.98 | -3.20 | -1.41 | -0.75 | -0.52 | -0.59 |
| SE | 0.14 | 0.19 | 0.19 | 0.17 | 0.14 | 0.13 | 0.14 | 0.15 | |
| LAZ | Mean | -8.78 | -8.34 | -5.93 | -4.46 | -2.34 | -1.37 | -1.07 | -0.34 |
| SE | 0.25 | 0.20 | 0.28 | 0.23 | 0.17 | 0.15 | 0.14 | 0.15 | |
| WLZ | Mean | -5.60 | -3.21 | -1.00 | -0.02 | -0.19 | -0.10 | -0.42 | -1.10 |
| SE | 0.39 | 0.39 | 0.21 | 0.17 | 0.17 | 0.13 | 0.15 | 0.21 |
Conclusion: ELBW who were fed preterm formula for 4-6 months had a significant fast postnatal growth pattern with normalization of their LAZ, WAZ, and WLZ during the first 12-18 months of life. Catch-up in LAZ continues during the third year of life.
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