ESPE2022 Poster Category 2 Growth and Syndromes (44 abstracts)
Postnatal growth in Preterm infants as a function of their weight for gestational age (GA) (WAZ) at birth: Comparison between those who were born underweight (WAZ <-2) compared to those with normal weight (WAZ > -2)
Fawzia Alyafei , Ashraf Soliman , Fatima Alkhori , Saleha Abbso , Doaa AlYousef , Mona Shaat , Maya Itani & Nada Alaaraj
Hamad General Hospital, Doha, Qatar
Introduction: Small size at birth is only a proxy for the pathological process of intrauterine growth restriction.
Aim: To study the effect of different birth weights on postnatal growth.
Method: We studied the linear growth of 59 infants who were born preterm (GA = 33.5 +/- 2.2 weeks) with birth weight >1.5 < 2.5 kg) for two years. They were classified at birth into two groups (group 1 with WAZ <-2) (underweight) and (group 2 with WAZ > -2).
Results: Preterm infants with birth WAZ <-2 increased their WAZ at 6 months and 12 months from -2.8 to -1.5 and -1.1 respectively. After an initial decrease in LAZ during the first 6 months of life from -1.5 to -1.7 they had LAZ catch up at the next 18 months (from -1.5 to -0.2). Their WLZ increased markedly from -5 at birth to -0.6, - 0.84, and -0.47 at 6, 12, and 24 months respectively. Preterm infants with birth WAZ > -2 had decreased WAZ during the first 6 months from -0.48 to -1.35. This was followed by a gradual increase of WAZ at 12, 18, and 24 months (-0.48, -0.28, and -0.1 respectively. Their LAZ decreased significantly during the first 6 months (from 0 to -1.7). During the next 18 months, LAZ increased to -1.1, -0.9, and -0.5 at 12, 18, and 24 months. WLZ increased from -4 at birth to -0.5, -0.12, and 0.25 at 6, 12, and 18 months respectively. Despite the significantly decreased LAZ and WLZ scores in the group with WAZ < -2 at birth, at two years none of the growth parameters (WAZ, LAZ, and WLZ) differ significantly between the two groups.
| birth | 6 months | |||||||
| Gest age | WTSD | LSD | WT/L | WTSD | LSD | WT/L | ||
| WTSD <-2 | Mean | 36* | (-2.83) * | (-1.48) * | -4.95 | -1.49 | -1.71 | -0.56 |
| N= 09 | SD | 2.50 | 0.38 | 0.51 | 2.61 | 0.91 | 1.08 | 1.63 |
| WTSD >-2 | Mean | 33.14 | -0.48 | -0.04 | -3.96 | -1.35 | -1.68 | -0.42 |
| N= 47 | SD | 1.68 | 0.96 | 1.26 | 1.14 | 1.28 | 1.17 | 1.41 |
| P-value | 0.0079 | <0.000001 | <0.000001 | 0.323 | 0.703 | 0.949 | 0.846 | |
| 12 months | 8 months | 24 months | ||||||
| WTSD | LSD | WT/L | WTSD | LSD | WT/L | WTSD | LSD | WT/L |
| -1.07 | -0.84 | -0.84 | -0.95 | -0.75 | -1.20 | -0.70 | -0.16 | -0.47 |
| 1.09 | 1.11 | 1.33 | 1.19 | 34.29 | 1.45 | 1.41 | 1.25 | 1.01 |
| -0.48 | -1.09 | -0.12 | -0.28 | -0.91 | 0.25 | -0.37 | -0.51 | -0.10 |
| 1.37 | 1.35 | 1.19 | 1.34 | 1.33 | 1.15 | 1.32 | 1.73 | 1.41 |
| 0.177 | 0.585 | 0.264 | 0.152 | 0.77 | 0.084 | 0.522 | 0.569 | 0.507 |
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