ESPE2022 Poster Category 2 Growth and Syndromes (44 abstracts)
Postnatal growth in Preterm infants as a function of their head size (head circumference Z score (HCZ) at birth: Comparison between those who were with a large head (HCZ <-2) to those with normal Head size for gestational age (HCZ > -2)
Fawzia Alyafei , Ashraf Soliman , Doaa AlYousef , Mona Shaat , Maya Itani , Noor Hamed , Shayma Ahmed & Hamdy Ali
Hamad General Hosptial, Doha, Qatar
Suboptimal head growth in utero and in early neonatal life may affect linear growth and weight gain during infancy. We studied linear growth and weight gain of 56 preterms (GA = 33.5 +/- 2.2 weeks) with birth weight >1.5 < 2.5 kg) for two years. They were classified at birth into two groups (group 1 with HCZ <-1) (relatively small head for GA) (35 +/- 2 weeks) and group 2 with HCZ > -1 (GA = 33 +/- 1.7 weeks)
Results: Preterm infants with birth HCZ <-1 increased their HCZ from -1.95 at birth to -1.5, -1.1, and -1.1 at 6, 12, 18, and 24 months. Their WAZ at 6 months, 12 months, and 24 months from -2.16 to -1.8, -1.4, and -1.1 respectively. They had a maximum catch-up in LAZ during the second 6 months of the first year. After an initial decrease in LAZ during the first 6 months of life from -1.5 to -1.7 they had a normal gain in length. Preterm infants with birth HCZ > -1 had a significant catch-up in WAZ at the end of the first year, WAZ was stable (normal weight gain) during the second year. LAZ increased progressively from -3.5 at birth to -1.6, -1.04, -0.75 and -0.25 at 6,12.18, and 24 months respectively.
| birth | 6 months | |||||||
| Gest age | WTSD | LSD | WLZ | WTSD | LSD | WLZ | ||
| HCSD <-1 | Mean | 34.77* | -2.16* | -1.54* | -4.76 | -1.82 | -2.04 | -0.72 |
| N= 14 | SD | 1.70 | 0.81 | 0.62 | 2.12 | 1.06 | 1.45 | 1.53 |
| HCSD >-1 | Mean | 32.89 | -0.42 | -3.53 | -3.90 | -1.23 | -1.57 | -0.34 |
| N= 42 | SD | 1.72 | 1.05 | 1.28 | 1.14 | 1.25 | 1.05 | 1.40 |
| P-value | <0.01 | <0.000001 | <0.000001 | 0.183 | 0.0961 | 0.138 | 0.485 | |
| 12 months | 18 months | 24 months | ||||||
| WTSD | LSD | WLZ | WTSD | LSD | WLZ | WTSD | LSD | WLZ |
| -1.4* | -1.06 | -1.1* | -1.36* | -1.30 | -0.99* | -1.1 * | -0.99* | -0.50 |
| 1.02 | 1.67 | 1.08 | 1.02 | 1.34 | 1.22 | 1.07 | 1 | 1.27 |
| -0.29 | -1.04 | 0.11 | -0.06 | -0.75 | 0.40 | -0.19 | -0.25 | 0.00 |
| 1.32 | 1.17 | 1.12 | 1.28 | 1.31 | 1.10 | 1.33 | 1.1 | 1.38 |
| 0.0024 | 0.971 | 0.004 | 0.000614 | 0.15 | 0.0059 | 0.0146 | 0.02 | 0.327 |
Conclusion: At birth, preterm infants with smaller HCZ were significantly shorter and lighter compared to those with bigger HCZ. At the end of the first and second years of life, the group with larger HCZ at birth was still significantly taller and heavier compared to the group with smaller HCZ at birth.
Article tools
My recent searches
My recently viewed abstracts
Authors
ESPE Abstracts
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more