ESPE Abstracts

The incidence of TIDM varies greatly between different countries and regions. In Navarre, located in the north of Spain, at the western end of the Pyrenees, there has been a clear increase in the incidence of TIDM, from 13,5 cases per 100000 in the decade 1990-2000 to 20,1 cases per 100000 between 2006-2011. We wonder if this upward trend has continued in recent years. Our hospital is a reference center for Pediatric Endocrinology in Navarre.

Objetives: Update the incidence of TIDM in Navarre of children under 15 years of age between January 2012 and December 2022.

Material and methods:• Capture-recapture methodology has been applied, using as primary source the tertiary and secondary hospitals in Navarre, and as secondary source the data from other hospitals (private, limiting communities), primary care centers and the diabetes association of Navarre •Statistical analysis: SPSS

Results: During the 11 years analyzed, 248 patients were diagnosed (145M/103F), mean age 8,80±3,85 years and mean incidence rate 22,42 cases per 100.000 person-year (95% CI: 21,7-23,1), increasing to 31,7 cases in the last two years. The incidence by age group was: 10-14 years (30,3), 5-9 years (22,99) and 0-4 yr (13.2). Of the cases, 25,5% of the cases were immigrants with a predominance of the North African population. As for seasonality, there were no differences (winter 26%, spring 26%, summer 25% and autum 23%). 35.9% of the patients had diabetic ketoacidosis at onset: mild (19,4%), moderate (6,8%) and severe (9,7%). DKA is significantly higher in the 10-14 (42%) and 0-5 age groups (41% each) vs. the 5-10 age group (19%) (P<0.05). Children of immigrant origin significantly debut at a younger age with higher percentage of DKA (P<0.05)

Conclusions: The incidence of in Navarre is high according to the WHO classification, with a progressive increase in recent years. There is a high proportion of patients with mild DKA, especially at early ages and puberty. Finally, it is worth noting the high incidence of the Maghreb population, especially in children under 5 years of age.