ESPE Abstracts (2023) 97 P1-453

ESPE2023 Poster Category 1 Fat, Metabolism and Obesity (97 abstracts)

Echocardiographic assessment of periaortic fat thickness and its relationship to cardiovascular risk factors in children with simple obesity

Shereen Abdelghaffar 1 , Aya M. Fattouh 1 , Ola Ali Mohamed 2 & Noha Arafa 3

1Faculty of Medicine, Cairo University, Cairo, Egypt. 2Ministry of Health, Assuit, Assuit, Egypt. 3Children's Hospital, Pediatric Department Faculty of Medicine, Cairo University, Cairo, Egypt

Key words: Childhood, Obesity, Periaortic fat thickness, Echocardiography, Cardiovascular risk.

Aim: To assess the periaortic fat thickness (PAFT) by echocardiograpy in a cohort of children with simple obesity and to evaluate its relationship to clinical and metabolic cardiovascular risk factors.

Methods: Fifty children and adolescents with simple obesity and 25 healthy sex and age matched controls were enrolled in the study. Periaortic fat thickness (PAFT) was measured by conventional echocardiography. Anthropometric measurements, and assessment of blood pressure status were performed. All participants were subjected to basal evaluation of plasma insulin, glucose, and lipid profile and underwent oral glucose tolerance test (OGTT).

Results: PAFT (axial, sagittal) were significantly higher among obese group (2.41+ 0.51mm), (2.08+ 0.51) than controls (1.76+0.34), (1.57+ 0.35) (p values<0.001). In children with obesity, PAFT was significantly correlated with diastolic blood pressure, systolic blood pressure, body mass index (BMI), waist circumference (WC), cholesterol levels, fasting plasma glucose, 2-hours postprandial glucose, fasting insulin, and Homeostatic model assessment insulin resistance (HOMA-IR). There was significant increase in septal wall thickness, left ventricular end diastolic diameter (LVEDD), and left atrial diameter among obese children than the controls (p values 0.001,0.003, 0.003) respectively.

Conclusion: Conventional echocardiography is a useful method for early detection of subclinical cardiovascular morbidities in pediatric obesity. The measurement of PAFT by conventional echocardiography is easy and convenient method for early prediction of atherosclerotic changes among obese children.

Volume 97

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

European Society for Paediatric Endocrinology 

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