ESPE2023 Poster Category 1 Fat, Metabolism and Obesity (97 abstracts)
Association of Serum Uric Acid Levels with Metabolic Syndromes in Children and Young Adolescents
Young Suk Shim 1 , Young-Jun Seo 2 , Hae Sang Lee 1 , Hwal Rim Jeong 3 , Jung Sub Lim 4 & Jin Soon Hwang 1
1Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea, Republic of. 2Department of Pediatrics, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea, Republic of. 3Department of Pediatrics, College of Medicine, Soonchunhyang University, Cheonan, Korea, Republic of. 4Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea, Republic of
Purpose: We investigated uric acid reference values and their association with cardiometabolic risk among children and adolescents using the Korea National Health and Nutrition Examination Survey (KNHANES).
Methods: A total of 2,462 participants, aged 10-18 years, from the KNHANES 2016-2018 were included.
Results: Serum uric acid (SUA) levels varied with sex and age. In male subjects, SUA levels tended to increase from 10 to 14 years of age and plateaued after 14 years of age. Moreover, the overall uric acid level in females was found to be lower than that in males; the levels tended to increase at approximately 10 to 12 years old but were relatively consistent according to age. Mean uric acid levels increased according to obesity status in both males and females. However, correlation analysis revealed that SUA levels were associated with several metabolic risks even after adjusting for obesity. The detailed metabolic syndrome (MetS) components that were observed to be associated with an increase in uric acid levels were different between males and females, but overall, high uric acid levels increased MetS risk. Additionally, a statistically significant increase in the OR for MetS and its components, such as waist circumference (WC), triglyceride (TG) levels, and low high-density lipoprotein cholesterol (HDL-C) levels, was observed.
Conclusion: SUA levels were closely associated with MetS and its components, even in non-obese subjects. Therefore, high SUA levels in children and young adolescents should be closely monitored to prevent MetS.
Article tools
My recent searches
My recently viewed abstracts
ESPE Abstracts
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more