hrp0098p3-47 | Diabetes and Insulin | ESPE2024

Children with Type 1 Diabetes and their families Satisfaction with Healthcare Services

Atwa Hoda , Omran Ahmed , Mustafa Omnia

Patient satisfaction is of increasing importance and is widely recognized as an indicator of quality of medical care. The aim was to assess children with type 1 diabetes and their families Satisfaction with Healthcare Services.Methods: The study was conducted at Pediatric outpatient clinic, Suez Canal University Hospital, Ismailia Egypt. Eighty children diagnosed with type 1 diabetes for at least 1 year. They were interviewed to obtain t...

hrp0084p3-965 | GH & IGF | ESPE2015

Effect of Human Growth Hormone on Growth Rate of Short Stature Children with Low Birth Weight

Saffari Fatemeh , Hassani Hoda , Esmailzadehha Neda , Javadi Amir

Background: If children with intrauterine growth retardation (IUGR) are stunt after birth, they will not have the desired height. Short stature is not fatal but affects personality and social and physical development of children.Objective and hypotheses: The aim of this study was to determine the effect of human GH on growth rate of short stature children with history of low birth weight.Method: This study was conducted on 148 chil...

hrp0097p1-54 | Fat, Metabolism and Obesity | ESPE2023

Early corneal nerve fiber regeneration in children with obesity and impaired glucose tolerance treated with the GLP-1 agonist Liraglutide

Gad Hoda , Dauleh Hajar , Pasha Maheen , A. Malik Rayaz , Hussain Khalid

Background: Glucagon-like peptide-1 receptor (GLP-1R) agonists are approved for the treatment of T2DM and obesity and high dose liraglutide is FDA approved for chronic weight management in pediatric patients aged 12 and older who are obese. GLP-1R may also have a beneficial effect on the central and peripheral nervous system. Corneal Confocal Microscopy (CCM) has been used to show early nerve fiber regeneration in adults with obesity with and without diabetes....

hrp0084p2-252 | Diabetes | ESPE2015

Brachial Flow Mediated Dilation and its Relation to Osteoprotegerin in Type 1 Diabetes Mellitus

Sherief Eman , Youssef Omneyia , El-Tawab Karim Abd , Ez-elarab Hoda , Ibrahim Moaz , Amr Nermine

Background: Type 1 diabetes is a risk factor for cardiovascular disease. Osteoprotegerin is a predictor of cardiovascular disease. Endothelial dysfunction is the earliest event in atherosclerosis and subsequent cardiovascular disease. Flow mediated dilation (FMD) of brachial artery can be used to detect endothelial dysfunction.Objective and hypotheses: To assess FMD of brachial artery in Type 1 diabetes and its relation to serum osteoprotegerin level.</p...

hrp0097rfc3.3 | Fat, metabolism and obesity 1 | ESPE2023

Early Corneal Nerve Loss in Children with Melanocortin 4 Receptor (MC4R) Gene Mutation Related Obesity

Gad Hoda , Dauleh Hajar , Pasha Maheen , Omer Idris , Al-Barazenji Tara , Alshafai Mashael , A. Hendaus Mohamed , A. Malik Rayaz , Hussain Khalid

Background: Obesity is highly prevalent worldwide, particularly in the MENA region. Whilst simple obesity has a variable genetic and environmental basis, syndromic and non-syndromic monogenic obesity has a strong genetic component. Melanocortin 4 receptor (MC4R) mutations are the commonest cause of monogenic obesity. MC4R also regulates neuropathic pain pathways via JNK signaling after nerve injury.Methods: Five children...

hrp0097p1-452 | Fat, Metabolism and Obesity | ESPE2023

Single center experience on using Liraglutide in adolescents with obesity +/- Type 2 diabetes

Dauleh Hajar , Pasha Maheen , Gad Hoda , Harris Basma , Khalifa Amal , Petroveski Goran , Afyoni Houda , Shehzad Saira , Chirayath Shiga , Mohamadsalih Ghassan , Mohammed Shaymaa , Malik Rayaz , Hussain Khalid

Background: Childhood obesity is recognized as a chronic illness with limited therapeutic options. Addressing this condition through lifestyle interventions has proven to be challenging, particularly for adolescents, with only minimal outcomes observed. The use of GLP-1 agonists (such as Liraglutide) for reducing body weight in pediatric patients has yielded conflicting results. To date, no studies conducted in the Middle East have reported on the outcomes of ...

hrp0098fc6.1 | Fat, Metabolism and Obesity 1 | ESPE2024

Corneal Nerve Loss and regeneration after GLP-1 Therapy in Children with Simple and Monogenic Obesity

Gad Hoda , Dauleh Hajar , Chirayath Shiga , Amin Rasha , Mohamadsalih Ghassan , Pasha Maheen , Mohammed Idris , Al-Barazenji Tara , Khalifa Amel , Petrovski Goran , Hamdoun Elwaseila , Al Bureshad Khalid , Ibrahim Marwa , A. Malik Rayaz , Hussain Khalid

Background: Obesity is highly prevalent in the MENA region, especially in children and it has been associated with neurodegeneration. We have undertaken corneal confocal microscopy (CCM) to assess for evidence of neurodegeneration in children with simple obesity and monogenic obesity (MC4R gene mutation) and further assessed the effect of glucagon-like peptide 1 agonist (GLP-1) therapy on corneal nerve regeneration.Methods:</stro...

hrp0097fc3.5 | Fat, metabolism and obesity 1 | ESPE2023

Early corneal nerve loss in children with obesity and type 2 diabetes

Gad Hoda , Dauleh Hajar , Chirayath Shiga , Pasha Maheen , Haris Basma , Amin Rasha , Afyouni Houda , Petrovski Goran , Shehzad Saira , Khalifa Amel , Mohammed Ahmed Elwaseila , Mohamadsalih Ghassan , Campbell Judith , Jolkka Sari , Biglang-awa Roshirl , Cuatrona Erlinda , Inso Gina , Razon Gerald , A. Hendaus Mohamed , Elgassim Einas , N. Petropoulos Ioannis , Ponirakis Georgios , A. Malik Rayaz , Hussain Khalid

Background: Childhood obesity is highly prevalent in the MENA region and may be associated with sub-clinical neuropathy.Methods: Children with obesity with normal glucose tolerance (NGT), impaired glucose tolerance (IGT) and Type 2 diabetes Mellitus (T2DM) and healthy controls (HC) underwent body composition analysis, assessment of vibration perception threshold (VPT), monofilament sensitivity and corneal confocal micros...

hrp0098p2-109 | Fat, Metabolism and Obesity | ESPE2024

Single-center experience in using a once weekly Semaglutide injection in adolescents with obesity +/- Type 2 diabetes

Dauleh Hajar , Amin Rasha , Pasha Maheen , Gad Hoda , Elshareif Tamara , Khalifa Amel , Petrovski Goran , Ahmed Elwaseila , Mohamadsalih Ghassan , Chirayath Shiga , Albureshad Khalid , Ibrahim Marwa , Campbell Judith , Hamdan Manar , Almajaly Douha , Umer Fareeda , Albahri Aya , Isamil Fatima , Saeed Sara , almasarweh Hadeel , cuatrona Erlinda , Biglangawa Roshirl , Inso Gina , Aler Joanna , A.Eyalawwad Ayah , Malik Rayaz , Hussain Khalid

Background: Childhood obesity presents a significant global health concern, leading to long-term morbidity and mortality. While lifestyle interventions remain fundamental, pharmacological approaches, particularly using glucagon-like peptide-1 (GLP-1) receptor agonists, show promise in certain patient populations. However, studies exploring this avenue, particularly in the Middle East and North African region, are limited. This study aims to share our experienc...