hrp0097p2-81 | Growth and Syndromes | ESPE2023

Small for age gestational: puberty status, metabolism and growth of an epipeg-premeb clinical cohort at 7-9 years after onset.

Diez-Lopez Ignacio , Sarasua Miranda Ainhoa , Maeso Mendenz Sandra , Etxebarria Aurrekoetxea Maialen

Objective: Observe in children born SGA the relationship that the different variables have in the evolution towards metabolic syndrome, adrenarche and/or early/advanced pubarche or short stature and treatment with GH.Material and Methods:A retrospective observational study analyzing in SGA children at birth (n=103) and who are currently between 7-9 years of age, variables such as: sex; “Catch UP&r...

hrp0097p2-170 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Vitamin D deficiency in pediatric population and influence on PTH levels

Diez-Lopez Ignacio , Sarasua Miranda Ainhoa , Maeso Mendez Sandra

Transversal study. Patients from 0 to 17 years of age who had undergone an analytical determination of 25OHD during the year 2021 in our hospital were collected. The following were contrasted: 25OHD, PTH, total calcium, age, sex, reason for requesting analysis, time of year and country of origin. 25OHD ranges: normal >30 ng/mL, suboptimal 20-30 ng/mL and deficit <20 ng/mL; and normal PTH: 9-60 pg/mL.Results: 1. Prevalence of vitami...

hrp0097p1-266 | Fat, Metabolism and Obesity | ESPE2023

Abdominal fat measured with nutritional ultrasound as a risk screening for non-alcoholic hepatic steatosis (NASH) in obese children

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Maeso Mendez Sandra , Garcia Casares Zuriñe , Erika Calvo Saez A

NASH is an increasingly relevant finding in the pediatric population affected by obesity. In adults, its evolution from this steatosis to fibrosis and its correlation with metabolic syndrome is increasingly significant. The existence of a rapid and validated screening tool in consultation would be very useful.Main objective: To evaluate if the measurement of intraperitoneal fat measured through nutritional ultrasound, allows the diagnosi...

hrp0097p2-166 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Value of antimullerian hormone (AMH) in the diagnosis of precocious puberty: revaluation of the covid-19 post-pandemic cohort

Diez-Lopez Ignacio , Aurora Vilella San Martín Leyre , Sarasua Miranda Ainhoa , San Martin Orayen Amaia , Maeso Mendez Sandra

During the pandemic, an increase in the cases of premature thelarche consultations was observed. Our group published a series in 2021 of 75 cases. This effect could have been caused by an increase in body fat mass in girls, suggesting a “trigger effect” in the activation of the gonadal axis, causing an increase in the number of cases of early puberty (SEEP Oviedo 2022). AMH has been correlated as a predictor of the moment of menarche (doi: 10.1515/jpem-2014-0521)</...

hrp0094p2-426 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

Uterus agenesia in a patient with CATCH 22 Syndrome. Purpose of a case

Ignacio Diez-Lopez , Mesonero Saray , Maeso Sandra , Sarasua-Miranda Ainhoa

Introduction: The CATCH 22 syndrome or DiGeorge syndrome or velocardiofacial syndrome, is a frequent pathology with the worldwide prevalence estimated between 1 / 2,000 and 1 / 4,000 live births. The classic clinic is characterized by typical facial features (narrow palpebral fissures, bulbous nasal tip, small mouth and ears, malar hypoplasia) with functional insufficiency of the soft palate in about 75% of those affected, difficulties in learning, language and behavior , cong...

hrp0094p1-149 | Sex Endocrinology and Gonads B | ESPE2021

Query By Telarquia: Has there been an increase due to the SARS-COV19 pandemic?

Vilella Leyre Aurora , Martin Amaia San , Maeso Sandra , Sarasua-Miranda Ainhoa , Diez-Lopez Ignacio ,

Have a real increase in precocious and advanced puberty with COVID19? Retrospective observational analytical study in which we compared the incidence of first consultations made by early thelarchies between the months of March to December 2019 and between March and December 2020 at the Pediatric Endocrinology(PE)consultation in our hospital, and the increase in diagnosis of precocious puberty (PP)and advanced puberty (PA) in the cases evaluated for this reason, with the aim of...

hrp0095p1-380 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Effect of Long Acting Gonadotropin Releasing Hormone Agonists on Height Outcome in Children

Sahmoud Shaimaa , Gupta Sanjay , Greetham Sandra

Gonadotropin releasing hormone agonists (GnRHa) stops premature sexual maturation in young children and preserve the potential of achieving acceptable adult height.Aim: To assess the efficacy of long acting GnRHa in suppressing early pubertal development and its impact on height outcome in our patient population.Methods: Records of children treated with GnRHa since 2018 at Hull University Hospital;...

hrp0082p3-d3-792 | Fat Metabolism &amp; Obesity (2) | ESPE2014

Frequency of Vegetable and Fruit Consumption in Overweight Children and Their Parents

Escobar Sandra Beatriz Escobar , Awadalla Shokery

Background: Increased incidence of obesity is related to increased consumption of fast and processed food and decreased consumption of fruits and vegetables.Objective and hypotheses: Evaluate the habit of fruit and vegetable consumption in children with overweight.Method: A questionnaire was designed in which the frequency and quality of these habits were recorded and anthropometric data also. Parent’s habits regarding fruit a...

hrp0097p2-15 | Growth and Syndromes | ESPE2023

Autosomal dominant inherited VUS 3 in the fibrillin 2 gene in a patient with tall stature

Geyrhofer Angelika , Hirtenlehner Sandra , Gencik Martin

Background: The reasons for tall stature, defined as a height above the 97. percentile or above 2SD from the mean, are heterogeneous. Besides non-pathogenic forms like familial tall stature or constitutional advance of growth there are pathogenic forms like obesity, growth hormone excess, hyperthyreoidism, precocious puberty or some genetic disorders and syndromes that need to be concerned.Case Report: We report on a 14 ...

hrp0092p1-218 | GH and IGFs (1) | ESPE2019

Lessons From a Patient Carrying Both an 11p Paternal Duplication and 15q Deletion, Illustrating the Roles of IGF2 and IGF1R in Growth Regulation

Brioude Frederic , Bastaraud Sandra Chantot- , Whalen Sandra , Netchine Irene , Giabicani Eloise

IGF2, a major actor which stimulates feta growth, is located within the imprinted 11p15 region, and 11p paternal duplications are usually associated with Beckwith Wiedemann syndrome, a rare condition usually associated with overgrowth. The IGF type 1 receptor binds both IGF-I and IGF-II to promotes cell proliferation and growth, and the IGF1R gene is located at chromosome 15q. Patients with deletions or mutations of IGF1R usually present with intraut...