hrp0094p1-37 | Fat, Metabolism and Obesity A | ESPE2021

The effect of trans-palmitoleic acid on lipid accumulation and the fatty acid synthase gene expression in hepatocytes

Nourbakhsh Mitra , Farokh-Nezhad Ramesh , Razzaghy-Azar Maryam , Sharifi Roya , Yaghmaei Parichehreh , Nourbakhsh Mona ,

Introduction: Obesity is among the most prevalent health problems and is associated with increased risk of various metabolic disorders, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Fatty acids comprise a major part of the lipids and have remarkable effect on cell biology. Trans fatty acids (tFAs) are generally a by-product of manufacturing of fats. However, naturally-produced tFAs that are found in milk and dairy products, are sugge...

hrp0092p3-105 | Fat, Metabolism and Obesity | ESPE2019

The Interaction Between Lipids Regulatory Genes Polymorphism and Obesity on Cardiometabolic Risk Factors in Children and Adolescents

Hashemipour Mahin , Hovsepian Silva , Kelishadi Roya

Objectives: It is suggested that interaction of dyslipidemia related polymorphisms with obesity is one of the possible mechanisms of expression of cardiometabolic risk factors in obese children. In this study, in order to classify high risk obese children and consequently prioritize health care resources for better management of childhood obesity,we investigated the outcome of GCKR(rs780094), GCKR(rs1260333), MLXIPL(rs3812316) and FADS(<a href="http://www.ncbi...

hrp0086p2-p301 | Diabetes P2 | ESPE2016

HbA1C and IGF-1 Levels in Diabetic Children Treated with Vitamin D

Dehkordi Elham Hashemi , Dehkordi Vida Hashemi , Fatemi Saied Mohammad Reza , Kelishadi Roya

Background: Diabetes mellitus type 1 (T1DM) is the most common chronic diseases in children. Studies show that the prevalence of vitamin D deficiency is higher in this group of patients.Objective and hypotheses: The aim of this study was evaluation HbA1C and IGF-1 levels in children with T1DM that receiving vitamin D supplement.Method: A total of 30 diabetic children 5–15 years with 25(OH) D levels lower than 74 nmol/l (29 ng/...

hrp0094p2-292 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Timing of infancy-childhood growth spurt in healthy Turkish children

Sharifova Sabina , Turan Hande , Tarcin Gurkan , Sharifli Samir , Gur Emel , Ercan Oya ,

Aim: The onset of the infancy-childhood growth spurt (IC spurt) is identical with the onset of the childhood component of the infancy-childhood-puberty growth model. The aim of this study was to determine the timing of IC spurt and to investigate the factors affecting it in healthy children.Materials and Methods: The files of 231 healthy children who were followed up regularly (at 0, 2, 4, 6, 12, 15, 18, 24, 30 and 36 months) at the Ista...

hrp0092fc9.5 | Fetal, Neonatal Endocrinology and Metabolism (to include Hypoglycaemia) | ESPE2019

Iodine Status of Pregnant Women and Their Newborns in the UK – the MABY Study

Bouga Maira , Redway Martha , Çizmecioglu Filiz Mine , Fletcher Suzanne , Sharif Sahar , H. Jones Jeremy , Donaldson Malcolm , Combet Emilie

Iodine is an essential dietary micronutrient required for thyroid hormone synthesis and neurodevelopment in utero. Evidence of iodine insufficiency among British women is of particular concern in the context of pregnancy. The Mothers and Babies at Yorkhill (MABY) study is a Glasgow-based longitudinal cohort study assessing the iodine and thyroid status of pregnant women and their offspring.Pregnant women were recruited from antenatal clinics (20...