hrp0098p2-104 | Fat, Metabolism and Obesity | ESPE2024

Silent Dangers: How Insulin Resistance and Trimethylamine N-Oxide Fuel Early Atherosclerosis in Obese Children. A preliminary study

Simina Mihuta Monica , Stoian Dana , Paul Corina

Introduction: Insulin resistance accelerates the onset of atherosclerosis and arterial stiffness in children. Trimethylamine N-oxide (TMAO), a gut-derived metabolite linked to cardio-metabolic issues in adults, could exacerbate these conditions in children as well. This study explores how insulin resistance and serum TMAO levels relate to vascular damage in obese children.Methods: We included 60 children aged 6 to 18, di...

hrp0095p1-142 | Multisystem Endocrine Disorders | ESPE2022

Two causes of short stature and delayed puberty in one patient: craniopharyngioma and celiac disease. A case report.

Simina MihutaMonica , Stoian Dana , Cepeha Cristina , Paul Corina

Introduction: Craniopharyngioma, a benign tumor, develops in the sellar/parasellar region. Diagnosis is usually late. Symptoms include severe headaches and vomiting, visual impairment, visual and olfactory hallucinations and at least one hormonal deficiency. Celiac disease is caused by an immune reaction triggered by gluten in the small intestine. Over time, due to inflammation, it causes malabsorbtion which can affect growth in children.<p class="abstext"...

hrp0095p2-123 | Fat, Metabolism and Obesity | ESPE2022

Diagnosis and management of childhood obesity during COVID-19 pandemic: an audit on clinical practice in a tertiary center

Pop Raluca-Monica

Background: Childhood obesity represents an important public health problem and its diagnosis and management should be based on current guidelines. Prevalence of childhood obesity in Romania is one of the lowest in Europe but with a positive trend.Aim: The aim of the current study was to analyze the implementation of the recommendations of the 2017 Endocrine Society Clinical Practice Guideline on Assessment, Treatment an...

hrp0092p3-114 | Fat, Metabolism and Obesity | ESPE2019

Rare Case of Acquired Generalized Lipodystrophy in A 14-Year Old Patient

Cristina Patricia Dumitrescu , Monica Mailat

Background: Lipodystrophies are a group of rare disorders characterized by varying degrees of body fat loss. The metabolic abnormalities associated with lipodystrophy include insulin resistance, often leading to diabetes mellitus, hypertriglyceridemia that may be severe enough to cause acute pancreatitis and hepatic steatosis that may lead to cirrhosis.They can be either genetic or acquired, generalized or partial. Acquired generalized l...

hrp0095p1-81 | Fat, Metabolism and Obesity | ESPE2022

The relationship between body mass index, adipose indices measured by whole-body DXA and markers of cardio-metabolic risk in survivors of childhood medulloblastoma

Cima Luminita-Nicoleta , Iliescu Marina , Soare Iulia , Nedelea Lavinia , Oprescu Raluca , Tarna Mihaela , Comsa Codruta , Dragomir Monica , Gabriela Barbu Carmen , Fica Simona

Background: Endocrine disturbances are the most prevalent complications in childhood cancer survivors (CSS), especially in those treated with cranial and cervical radiation for brain tumours, such as medulloblastoma. Recent data have shown frequent delays in the diagnosis and treatment of these complications that may lead to potential side-effects on general health. Apart from the well-known hypothalamic–pituitary and growth disorders observed in CSS, th...

hrp0092p2-117 | Fat, Metabolism and Obesity | ESPE2019

Trends in Childhood Obesity, Underweight and Short Stature Among Urban School Children in Romania

Pop Raluca-Monica , Neagu Nicolae , Pascanu Ionela

Background: Childhood adolescence overweight and obesity are increasing in Romania, but limited information is available on their current trends.Aim: the current study aimed to analyze the trend in prevalence of weight disturbances and stunting in the past 5 years in school aged children from the Transylvania region in Romania.Material and Methods: Two cross-sectional data sets fro...

hrp0086p2-p846 | Syndromes: Mechanisms and Management P2 | ESPE2016

Should We Construct Specific Growth Charts for Ethnic Subgroups?

Pop Raluca-Monica , Pascanu Ionela Maria

Background: Romania has a 3.3% Rromanes population according to the latest census, but no specific growth charts for this ethnic minority. Current national protocol recommends using the Swiss growth charts developed in 1989. Specific growth charts exist for ethnic subgroups like Turks in Germany and the Netherlands.Objective and hypotheses: A comparison between a Rromanes and a Romanian group of children regarding weight and height disturbancesÂ’ pre...

hrp0082p3-d1-822 | Growth | ESPE2014

Auxological Evaluation of ‘Non-Identical Twins’

Pop Raluca-Monica , Pop Marian , Pascanu Ionela

Background: Multiple external influences have proved to be of importance in auxology. Sub-group analysis can identify specific factors involved in normal children development.Objective and hypotheses: The main objective of the study was to identify differences in development in children born the same day from different parents. Our hypothesis was that there are identifiable general factors that predict the growth of a child.Method:...

hrp0082p3-d2-856 | Growth (3) | ESPE2014

Anthropometric Evaluation of a Cohort of School-Aged Children: the Need for National Growth References in Romania

Pop Raluca-Monica , Pascanu Ionela , Pop Marian

Background: For children above 5 years of age no specific national growth charts are available in our country, the most widely used being the Swiss ones (Prader, 1989). Previous studies have shown significant differences between the various international standards available regarding. The incidence of growth disorders.Objective and hypotheses: Our aim was to compare the recommended growth reference with a new one based on a national representative sample...

hrp0095p1-589 | Thyroid | ESPE2022

Familial Dysalbuminemic Hyperthyroxinemia (FDH) in Asymptomatic Child with High Free T4 and Normal TSH

Shanza Afzaal Shanza , Aljalily Sarraa , Malheiros - França Monica , Ten Svetlana

Case report: 6 yrs. old boy presented with high total T4, free T4, reverse T3, and normal total T3 and TSH. He has a history of tic disorder. Blood pressure, and heart rate were normal, no palpitations, no weight loss. Thyroid peroxidase and thyroglobulin antibodies were normal. Thyroid sonogram was normal. Family is of Hispanic origin. There was a family history of elevated T4 in the paternal uncle (half-brother of the father)Me...