hrp0094p2-388 | Pituitary, neuroendocrinology and puberty | ESPE2021

Central precocious puberty: clinical, etiologic and therapeutic features

Assarrar Imane , Derkaoui Nada , Rami Imane , Rouf Siham , Latrech Hanane ,

Introduction: Precocious puberty is defined by the apparition of secondary sexual features before the age of 8 years in girls and 9.5 years in boys. Central precocious puberty (CPP) results from a premature activation of the hypothalamic-pituitary-gonadal axis. The aim of this study is to review the clinical, etiologic and therapeutic features of this entity.Patients and methods: It is a descriptive retrospective study including 7 patien...

hrp0098p2-364 | Late Breaking | ESPE2024

The Influence of puberty timing on the development of metabolic Syndrome in Turner Syndrome patients.

Yagoubi Latifa , Ourdi Amal , Bouichrat Nisrine , Rouf Siham , Latrech Hanane

Introduction: Turner syndrome (TS) is a genetic disorder characterized by the partial or total absence of an X chromosome. It is the most frequent sex chromosome abnormality in females (1). Patients with TS are susceptible to a variety of metabolic abnormalities. Puberty is a sensitive phase of both physical and hormonal development, and its timing can impact the development of metabolic syndrome. This study aims to clarify the impact of the onset of puberty o...

hrp0098p3-290 | Late Breaking | ESPE2024

The Impact of Insulin-Induced Lipodystrophy on Glycemic Variability in Pediatric Patients with Type 1 Diabetes

Bakmizi Hanae , Hamdane Chaymae , Salhi Asmae , Rouf Siham , Latrech Hanane

Introduction: Lipodystrophy is the most common dermatological complication in patients with diabetes receiving insulin therapy. Despite the high incidence of lipodystrophy, there are still some difficulties in the practical implementation of prevention recommendations in children and adolescents with type 1 diabetes and their caregivers. This cross-sectional study aims to assess the prevalence of insulin-induced lipodystrophy in a cohort of pediatric patients ...

hrp0095p2-79 | Diabetes and Insulin | ESPE2022

Association of type 1 diabetes mellitus with autoimmune diseases in children in the Department of Endocrinology-Diabetology and Nutrition at Mohammed VI University Hospital Center Oujda

Charif Hajar , Yagoubi Latifa , Ourdi Amal , Youssra Laalaoua , Assarar Imane , Messaoudi Najoua , Rouf Siham , Latrech Hanane

Introduction: Type 1 diabetes is frequently accompanied by other autoimmune diseases that can sometimes be integrated into autoimmune polyendocrinopathies. Through this work, we sought to describe the association of autoimmune diseases with type 1 diabetes in children.Patients and Methods: This is a retrospective and descriptive study, including 354 type 1 diabetic patients hospitalized in the Department of Endocrinology...

hrp0095p2-86 | Diabetes and Insulin | ESPE2022

Type 1 diabetes in children: What are the particularities?

Ourdi Amal , Hajar Charif , Latifa Yagoubi , Najoua Messaoudi , Soumia Berrabeh , Siham Rouf , Hanane Latrech

Introduction: Children’s type 1 diabetes is a rare entity, its prevalence is still poorly known, which makes its diagnosis, therapeutic management and prognosis increasingly difficult and uncodified. The purpose of our study is to report the experience of the Endocrinology - Diabetology and Nutrition Department in the management of diabetes in children.Methods: This is a retrospective, descriptive study including 1...

hrp0095p2-88 | Diabetes and Insulin | ESPE2022

Association of type 1 diabetes mellitus with autoimmune diseases in children in the Department of Endocrinology-Diabetology and Nutrition at Mohammed VI University Hospital Center Oujda

Charif Hajar , Yagoubi Latifa , Ourdi Amal , Laalaoua Yousra , Assarrar Imane , Messaoudi Najoua , Rouf Siham , Latrech Hanane

Introduction: Type 1 diabetes is frequently accompanied by other autoimmune diseases that can sometimes be integrated into autoimmune polyendocrinopathies. Through this work, we sought to describe the association of autoimmune diseases with type 1 diabetes in children.Patients and Methods: This is a retrospective and descriptive study, including 354 type 1 diabetic patients hospitalized in the Department of Endocrinology...

hrp0095p2-157 | GH and IGFs | ESPE2022

Prevalence of Childhood Short Stature and weight variations Among Primary School Children

Berrabeh Soumiya , Bouali Houda , Boujtat Khadija , Assarrar Imane , Rouf Siham , Latrech Hanane

Keywords: short stature, underweight, overweight, obesityIntroduction: Natural growth is an important indicator of health in childhood. Growth retardation can result from systemic and endocrine diseases or poor diet. Being overweight or obese in childhood increases the risk of morbidity and mortality in adulthood. This study, the first of its kind in Morocco, was conducted to compare the prevalence of growth disorders am...

hrp0095p2-195 | Growth and Syndromes | ESPE2022

Syndromic Disorders with Short Stature

Zerrouki Dounia , Alla Achwak , Rami Imane , Derkaoui Nada , Benyekhlef Salma , Rouf Siham , Latrech Hanane

Keywords: Short stature, Noonan syndrome, Prader-Willi syndrome, Silver-Russell syndrome, genetic syndromesIntroduction: Short stature is one of the major components of dysmorphic syndromes. Growth failure may be due to a wide variety of mechanisms, either related to the growth hormone (GH)/insulin-like growth factor axis or to underlying unknown pathologies. At present, GH therapy is used in most syndromic disorders, al...

hrp0095p2-209 | Multisystem Endocrine Disorders | ESPE2022

Fahr's syndrome in children: About 2 cases

Berrabeh Soumiya , Elmehraoui Ouafae , Messaoudi Najoua , Assarrar Imane , Rouf Siham , Latrech Hanane

Keywords: Basal ganglia calcifications, hypoparathyroidism, farh's diseaseIntroduction: Fahr syndrome is a rare anatomical-clinical entity, defined radiologically by the presence of bilateral, symmetrical, non-arteriosclerotic triatopallidodentate calcifications. Its diagnosis is radiological, and must be distinguished from Fahr's disease, which corresponds to the presence of calcifications without abnormalitie...

hrp0095p2-239 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Interest of LHRH test in the exploration of precocious puberty

Yagoubi Latifa , Assarrar Imane , Rami Imane , Charif Hajar , Ourdi Amal , Rouf Siham , Latrech Hanane

Introduction: We refer to precocious puberty when signs of puberty appear early: before the age of 8 in females and before the age of 9.5 in males. The objective of our study is to evaluate the interest of the LHRH test in the exploration of early puberty.Materials and Methods: A retrospective descriptive study including 19 cases who presented with signs of precocious puberty. A clinical and hormonal evaluation was perfo...