hrp0082p2-d3-497 | Endocrine Oncology | ESPE2014

Gonadal Tumor in 46,XY and 45,X/46,XY Female Patients: One Clinical Center Experience

Gawlik Aneta , Antosz Aleksandra , Kudela Grzegorz , Drosdzol-Cop Agnieszka , Zachurzok Agnieszka , Matusik Pawel , Kaminska Halla , Koszutski Tomasz , Malecka-Tendera Ewa

Background: The incidence of gonadal tumor development varies significantly between subsets of patients with disorder of sex development (DSD). In some female patients with Y chromosome too early gonadectomy is perceived as overtreatment.Objective and hypotheses: The aim of the study was to analyze the gonadal tumor incidence in DSD female patients with 45,X/46,XY or 46,XY.Method: 15 patients, managed at single institution between ...

hrp0092p1-131 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Is there the Relationship Between Anxiety and Depression Level and Clinical Presentation of Polycystic Ovary Syndrome in Adolescent Girls?

Zachurzok Agnieszka , Pasztak-Opilka Agnieszka , Malecka-Tendera Ewa

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of the young women, and it could influence both physical and psychological wellbeing. As a consequence of obesity and hirsutism lower sexual attractiveness, higher emotional distress as well as higher depression score is frequently observed.Study Objective was to evaluate anxiety and depression score as well as the body esteem and stress perception ...

hrp0086p2-p383 | Gonads & DSD P2 | ESPE2016

Thyroid Autoimmunity in Adolescent Girls with Polycystic Ovary Syndrome – Pilot Study

Zachurzok Agnieszka , Skrzynska Karolina , Gawlik Aneta , Malecka-Tendera Ewa

Relationship between polycystic ovary syndrome (PCOS) and thyroid autoimmunity has been recently suggested by several authors. Autoimmune thyroiditis (AIT) is the most prevalent autoimmune disease and link between AIT and PCOS has been reported in adult women. There is a hypothesis that functional autoantibodies could contribute to the development of PCOS. The aim of the study was to evaluate the prevalence of thyroid autoimmunity in adolescent girls with PCOS. Forty five adol...

hrp0098p1-137 | Fat, Metabolism and Obesity 2 | ESPE2024

Evaluation of VEGF, MMP-9 and visfatin levels in adolescent girls with polycystic ovary syndrome and abdominal obesity

Skrzyńska Karolina , Zachurzok Agnieszka , Gawlik-Starzyk Aneta

Introduction: Polycystic ovary syndrome (PCOS) prevalence varies widely, ranging from 2.2 to 20%, depending on the diagnostic criteria and the studied population. This condition increasingly affects adolescents, potentially affecting around 3-11% of girls. In three forth women with PCOS obesity is present, with elevated prevalence of central distribution of adipose tissue - a significant risk factor for various metabolic disorders. Recent studies have focused ...

hrp0089p2-p350 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P2 | ESPE2018

Psychological Gender Features and Social Abilities and in Adolescent Girls – Influence of Obesity and Hyperandrogenism

Zachurzok Agnieszka , Pasztak-Opilka Agnieszka , Forys-Dworniczak Elzbieta , Drosdzol-Cop Agnieszka , Gawlik Aneta , Malecka-Tendera Ewa

Background: Both, obesity and hyperandrogenism are the conditions that can influence many different health domains, also may affect the mental and social wellbeing components of subject’s life.Study objective: To evaluate whether body weight status and clinical hyperandrogenism may influence social competencies and psychological gender features in adolescent girls.Design & participants: In 104 adolescent girls clinical eva...

hrp0082p2-d2-329 | Diabetes (1) | ESPE2014

Lipid Profile is Related to Androgen Level in Adolescent Girls with Type 1 Diabetes Mellitus

Zachurzok Agnieszka , Deja Grazyna , Gawlik Aneta , Drosdzol-Cop Agnieszka , Malecka-Tendera Ewa

Background: The mechanisms underlying dyslipidaemia in the context of polycystic ovary syndrome may include not only metabolic aberrations but also hormonal factors, in particular hyperandrogenaemia.Objective and hypotheses: The aim of the study was to establish whether dyslipidaemia and metabolic control disturbances are related to hyperandrogenaemia in adolescent girls with type 1 diabetes mellitus (T1DM).Method: We studied 54 gi...

hrp0084p3-1205 | Thyroid | ESPE2015

Subclinical Hypothyroidism in Children and Adolescents – A 5-year Single-center Follow-up Study

Gawlik Aneta , Such Kamila , Dejner Aleksandra , Zachurzok Agnieszka , Antosz Aleksandra , Malecka-Tendera Ewa

Background: Most experts agree that subclinical hypothyroidism (SH) represents early, mild thyroid failure, however there are controversies about the evolution of SH over time.Objective and hypotheses: The aim of the study was to analyse the dynamics of thyroid dysfunction in children initially referred as patients with SH.Method: During the period January 2010 – January 2015, 258 unselected consecutive SH patients (140 girls)...

hrp0094p2-207 | Fat, metabolism and obesity | ESPE2021

Restriction of physical activity is the main cause of childhood obesity during the COVID-19 pandemic – reflections from a study conducted in 3 clinical centers in southern Poland

Zachurzok Agnieszka , Wojcik Małgorzata , Gawlik Aneta , Starzyk Jerzy B. , Mazur Artur ,

Background: The aim of this study was to analyze the impact of the COVID-19 pandemic lockdown on behaviors and subsequent changes in BMI in children from southern Poland.Methods: The study included 206 participants (104 females and 102 males) with a complete analysis of 177 (96 females and 81 males) with a mean age of 12.8 ± 2.6 years admitted to three pediatric endocrinology clinics (Rzeszów, Kraków, and ...

hrp0098p1-72 | Multisystem Endocrinology | ESPE2024

Serum nesfatin-1 and GLP-1 concentrations in adolescent patients with anorexia nervosa/obesity.

Blaska Małgorzata , Zachurzok Agnieszka , Gołąb-Jenerał Katarzyna , Ziora Katarzyna

Introduction: Anorexia nervosa (AN) is a psychiatric disorder affecting mainly adolescents and young women, characterized by a restriction of energy intake leading to malnutrition, serious medical complications and high mortality. Until now the etiology of AN remains unknown and seems to be multifactorial. Patients with AN develop endocrine disorders related to disturbances of energy metabolism. Nesfatin-1 and glucagon-like peptide-1 (GLP-1) are involved in th...

hrp0098p2-254 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Implication for metabolic heath of using of adolescent PCOS criteria

Malczyk Żaneta , Nowak Ciołek Maria , Stachowiak Julia , Krok Katarzyna , Sokal Julia , Skrzyńska Karolina , Zachurzok Agnieszka

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women. The diagnosis of PCOS in adolescent patients can be difficult because characteristics of normal puberty often overlap with signs and symptoms of PCOS. Irregular menstrual cycles and ultrasound display of multiple follicles are common finding during puberty. In recent years new diagnostic criteria for PCOS in adolescent females were introduced. These new criteria i...