hrp0095wg8.1 | ESPE Nursing and Allied Health Working Group (PENS) Symposium | ESPE2022

Benefits of multidisciplinary care in Prader-Willi syndrome

Amin Nadia

Prader-Willi syndrome (PWS) is a complex genetic disorder which affects endocrine and neurological systems, metabolism and behaviour. In the neonatal period PWS is characterised by hypotonia, and resultant failure to thrive, whilst in childhood hyperphagia and obesity typically predominate. Patients can develop hypothalamic dysfunction and a range of endocrinopathies, including growth hormone deficiency, hypogonadism and hypothyroidism. Patients with PWS benefit from early and...

hrp0089p2-p214 | GH & IGFs P2 | ESPE2018

Incidence of Cranial MRI Abnormalities in Patients with Isolated Growth Hormone Deficiency: 20 Years of Results

Amin Nadia , Biliaieva Kateryna , Mushtaq Talat

Background: Patients with isolated growth hormone deficiency (GHD) will routinely have an MRI scan of the pituitary and brain to assess pituitary size and presence of any intracranial lesions. The result may change the threshold for monitoring for further hormone deficiencies. However the test may also detect unexpected or unrelated abnormalitiesAim: To review the incidence of normal and abnormal MRI scans in children with a diagnosis of isolated GHD.</p...

hrp0095p2-2 | Adrenals and HPA Axis | ESPE2022

Retrospective cross-sectional study reviewing local practice in assessment of adrenal axis at a tertiary children’s hospital

Hester Holly , Hachemi Soraya , Amin Nadia , Alvi Sabah

Introduction: There is considerable variation in practice when assessing adrenal function in adrenal insufficiency; duration of glucocorticoid defined to confer risk, early morning cortisol assay (EMC), Synacthen test (ST) - both low dose (LDST) (1microgram) or standard dose (SDST) (36microgram/kg [maximum 250micrograms]) and symptomatology. At our tertiary children’s hospital, even between departments, there is variation in those identified as being at ...

hrp0089p3-p055 | Bone, Growth Plate &amp; Mineral Metabolism P3 | ESPE2018

The British OsteoNEcrosis Study: A Multi-centre Prospective Study

Amin Nadia , James Beki , Feltbower Richard , Mushtaq Talat , Kinsey Sally

Introduction: Osteonecrosis can be a debilitating consequence of treatment for acute lymphoblastic leukaemia (ALL), most commonly affecting patients aged between 10 and 20 years at diagnosis of malignancy. Patients may have asymptomatic lesions that spontaneously regress, and little is known about the natural history of lesions. There is also limited understanding of the relationship between osteonecrosis and other markers of bone health.Aims: The aims o...

hrp0084p2-284 | Diabetes | ESPE2015

In-Patient Care for Children with Type 1 Diabetes – A Regional Audit in the Yorkshire and Humber Region in the North of England

Uday Suma , Amin Nadia , Campbell Fiona , Yong James

Introduction: An important part of diabetes management is maintaining high standards of in-patient care. A previous audit in the South of England demonstrated difficulties consistently achieving standards identified as good practice.Objectives: To identify variations in in-patient care provided to children with type 1 diabetes across the Yorkshire and Humber region.Methods: The audit was conducted against in-patient care standards ...

hrp0097fc9.3 | Diabetes and insulin 2 | ESPE2023

A novel case of hypoglycaemia secondary to a pro-insulin processing disorder

Amin Nadia , Wark Gwen , Church David , Burling Keith , Barker Peter , Williams Gemma , O'Rahilly Stephen

Background: Hypoglycaemia in patients with a high concentration of insulin and low concentration of C-peptide can be secondary to administration of exogenous insulin. This often results in safeguarding measures, with significant consequences for the patient and family. We report a novel case of a patient with symptomatic hypoglycaemia. Initial results suggested high insulin and low C-peptide levels, but subsequent testing revealed a pro-insulin processing diso...