hrp0084p2-273 | Diabetes | ESPE2015

Utility of Estimated Glucose Disposal Rate and Fat Mass Percentage for Predicting Metabolic Syndrome in Children and Adolescents with Type 1 Diabetes

Koken Ozlem , Kara Cengiz , Yilmaz Gulay Can , Aydin Murat

Objective: To determine the prevalence of metabolic syndrome (MetS) and the clinical utility of fat mass percentage (%fat) and estimated glucose disposal rate (eGDR) for predicting MetS in children and adolescents with type 1 diabetes (T1D).Method: We conducted a descriptive, cross sectional study including T1D patients between 8–18 years of age. Modified criteria of IDF, WHO and NCEP were used to determine the prevalence of MetS. eGDR, a validated ...

hrp0084p1-153 | Miscelleaneous | ESPE2015

Growth Curves for Height, Weight, BMI and Head Circumference in Children with Achondroplasia

Dogan Murat , Aydin Ilyas , Bala Keziban Asli , Kaba Sultan , Gulpunar Ozlem

Background: Close monitoring of growth is vital when following children with achondroplasia yet existing growth curves suffer from a simple chart format and their clinical use is therefore limited. Also, references for body proportions; i.e. sitting height, relative sitting height and arm span, are lacking.Objective and hypotheses: The aim of this study was to construct age-specific growth curves for height, weight, BMI, head circumference and body propo...

hrp0084p2-238 | Bone | ESPE2015

Can Vitamin D Deficiency Cause Prolongation in Visual Evoked Potentials?

Dogan Murat , Aydin Ilyas , Kaba Sultan , Bala Keziban Asli , Gulpinar Ozlem

Objective: It is known that vitamin D has differential roles in cell proliferation, differentiation, neurotransmission and neuroplasticity in nervous system and exerts neurotrophic and neuroprotective effects. In recent studies, it was shown that vitamin D could be protective against in age-related macular degeneration and optic neuritis related to demyelinating disorders. Here, we aimed to perform visual evoked potential (VEP) studies before treatment in patients with rickets...

hrp0084p3-640 | Bone | ESPE2015

Cranial MR Spectrometry Findings of Patients Aged 10–15 Years with Diagnosis of Rickets

Dogan Murat , Aydin Ilyas , Bala Keziban Asli , Kaba Sultan , Gulpinar Ozlem

Objective: It is known that vitamin D has differential roles in cell proliferation, differentiation, neurotransmission and neuroplasticity in nervous system and exerts neurotrophic and neuroprotective effects, even different functions of vitamin D has been studied by advocating that vitamin D should be classified as a neurosteroid. It has been long known that vitamin D deficiency, VDR dysfunction, hyperparathyroidism and hypervitaminosis are potential causes for sensorineural ...

hrp0089p2-p011 | Adrenals and HPA Axis P2 | ESPE2018

Neonatal Screening for Congenital Adrenal Hyperplasia in Turkey: A Pilot Study with 38 935 Infants

Guran Tulay , Tezel Basak , Gurbuz Fatih , Eklioglu Beray Selver , Hatipoglu Nihal , Kara Cengiz , Sahin Nuran , Simsek Enver , Cizmecioglu Filiz Mine , Ozon Alev , Bas Firdevs , Aydin Murat , Ozdemir Gulsum , Darendeliler Feyza

Background: Congenital adrenal hyperplasia (CAH) is the most common form of primary adrenal insufficiency in children. 21-hydroxylase enzyme deficiency (21-OHD) occurs in 90–95% of all cases of CAH. Despite it being a treatable condition, if unrecognized, CAH may present with life-threatening cardiovascular collapse. Mortality in the first years is reported to be higher than in the general population. Neonatal screening for CAH is effective in detecting the salt-wasting f...

hrp0084p3-642 | Bone | ESPE2015

Comparison of Treatment Alternatives for Hypercalcemia due to Vitamin D Intoxication in Children

Demir Korcan , Doneray Hakan , Yesilkaya Ediz , Kara Cengiz , Atay Zeynep , Cetinkaya Semra , Cayir Atilla , Anik Ahmet , Eren Erdal , Demirel Fatma , Yilmaz Gulay Can , Ergur Ayca Torel , Kendirci Mustafa , Aycan Zehra , Bereket Abdullah , Aydin Murat , Orbak Zerrin , Ozkan Behzat

Background: No large study comparing efficiency of prednisolone, alendronate and pamidronate has been conducted so far in children with hypercalcemia due to vitamin D intoxication.Objective and hypotheses: To perform a multicentre, retrospective study assessing clinical characteristics and treatment results.Method: A standard questionnaire was uploaded to an online national database system (www.favorsci.org) to collect data of chil...

hrp0092p2-137 | Fat, Metabolism and Obesity | ESPE2019

Clinical Characteristics and Response to Growth Hormone Treatment in Patients with Prader-Willi Syndrome

Evliyaoglu Olcay , Dagdeviren Cakir Aydilek , Bas Firdevs , Akin Onur , Siklar Zeynep , Özcabi Bahar , Berberoglu Merih , Kardelen Asli Derya , Bayramoglu Elvan , Poyrazoglu Sükran , Aydin Murat , Ergül Türel Ayça , Göksen Damla , Bolu Semih , Aycan Zehra , Tüysüz Beyhan , Ercan Oya

Introduction and aim: Prader-Willi syndrome(PWS), is a genetic disorder caused by the absence of paternal genes located on chromosome 15q11.2-q13. In this multi-central study; patients with PWS were followed for 2 years. Initial clinical and laboratory findings, growth hormone(GH) treatments and their responses were evaluated.Patients and Methods: 54 patients from 10 pediatric endocrine centers were involved and data was...

hrp0084p2-580 | Thyroid | ESPE2015

The Diagnostic, Treatment and Follow-Up Features of Childhood Thyroid Malignancies – A Preliminary Report

Bideci Aysun , Yesilkaya Ediz , Berberoglu Merih , Siklar Zeynep , Darcan Sukran , Ozen Samim , Bas Serpil , Doger Esra , Eren Erdal , Turan Serap , Akinci Aysehan , Demirel Fatma , Simsek Enver , Cetinkaya Semra , Bircan Iffet , Aydin Murat , Bober Ece , Sari Erkan , Hatipoglu Nihal , Tayfun Meltem , Saglam Halil , Ozbek Mehmet Nuri , Yildirim Ruken , Dundar Bumin , Cayir Atilla , Alagoz Engin , Atas Erman

Background: Thyroid cancer is a very rare malignancy of childhood. Approximately they account for 1.5% of all cancers before 15 years of age. In our country, this rate is %0.4 before 20 years of age.Aims and objectives: To analyses the clinical features and treatment results of children with thyroid malignancy in Turkey.Methods: In this multicentric and retrospective study the demographic and clinical characteristics of 124 childre...

hrp0095p1-99 | GH and IGFs | ESPE2022

Survey to Investigate Adherence to Growth Hormone Treatment in Children: The Impact of COVID-19 Pandemic

Eren Erdal , Cetinkaya Semra , Denkboy Ongen Yasemin , Tercan Ummuhan , Darcan Sukran , Turan Hande , Aydin Murat , Yavuz Yilmaz Fatma , Kilci Fatih , Sever Eklioglu Beray , Hatipoglu Nihal , Yuksek Acinikli Kubra , Orbak Zerrin , Camtosun Emine , Savas Erdeve Senay , Arslan Emrullah , Ercan, Feyza Darendeliler Oya

Introduction: Treatment adherence is crucial for the success of Growth Hormone (GH) therapy. Non-adherence rates have varied over a wide range from 5% to 80% in the literature. Several factors may have an impact on treatment adherence. Besides, with the COVID-19 pandemic that affected the whole world, there were problems with the hospital admission and routine controls of the patients who used GH treatment.Objective: The...