hrp0095lb4 | Late Breaking | ESPE2022

The association between glycated albumin and HbA1c in pediatric acute leukemia patients

Yeun Sim Soo , Bae Ahn Moon , Suh Byung-Kyu

Introduction: Traditionally, HbA1c has been used as a preferred glycemic index in diabetes patients. However, as many acute leukemia patients often present with anemia and/or pancytopenia, HbA1c may not accurately represent blood glucose level in this group. Glycated albumin represents the average level of blood glucose in recent 2-3 weeks, independent of red blood cell life. In this study, we aim to evaluate the usefulness of glycated albumin as glycemic moni...

hrp0095p2-301 | Late Breaking | ESPE2022

Analysis of Factors Affecting Bone Mineral Density in Children and Adolescents with systemic lupus erythematosus

Jin Park Su , Bae Ahn Moon , Suh Byung-Kyu

Background: Children and adolescents with chronic disease are at risk of developing bone fragility. In particular, low bone mineral density (BMD) is increasingly recognized in pediatric patients with glucocorticoid treated rheumatic disease. The purpose of this study was to evaluate the clinical characteristics of children and adolescents with systemic lupus erythematosus (SLE), and to analyze the factors associated with a lower BMD in these patients.<p cl...

hrp0097p1-421 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Bisphosphonate, sirolimus, atenolol treatment in a 4-year old child diagnosed with Gorham-Stout disease

Jin Park Su , Yeun Sim Soo , Suh Byung-Kyu , Bae Ahn Moon

Gorham-Stout disease(GSD), also known as vanishing bone disease is an extremely rare skeletal disorder characterized by idiopathic intraosseous proliferation of lymphatic vascular structures resulting in progressive resorption of bone. Herein, we report a case of a 4-year-old girl with GSD treated with the combination treatment with bisphosphonate, sirolimus, and atenolol. A 4-year-old girl presented with prolonged back pain for 2 weeks. The thoracolumbar spine radiography rev...

hrp0097p1-32 | Diabetes and Insulin | ESPE2023

Continuous Glucose Monitoring: A possible aid to detect hypoglycemia event during insulin challenge tests

Yeun Sim Soo , Jin Park Su , Bae Ahn Moon , Suh Byung-Kyu

Combined pituitary function test is a dynamic function test used to evaluate the anterior pituitary gland in patients suspected with hypopituitarism. The test comprises insulin challenge test where intravenous insulin injection in order to induce symptomatic hypoglycemia (serum blood glucose <40mg/dL). Insufficient increase in growth hormone and cortisol after the stimulation confirms the diagnosis of growth hormone deficiency and/or adrenal function insufficiency. However,...

hrp0095p1-459 | Diabetes and Insulin | ESPE2022

Usefulness of glycated albumin level as a glycemic index complementing glycosylated hemoglobin in children and adolescents

Ju Choi Young , Jeong Jang Min , Shin Chungwoo , Bae Ahn Moon , Ho Jung Min , Suh Byung-Kyu

Introduction: Serum glycated albumin (GA) is a glycemic marker reflecting the average serum glucose values for the previous 2 weeks. The purpose of this study was to evaluate the usefulness of serum GA as a glycemic index complementing glycosylated hemoglobin (HbA1c) in children and adolescents.Methods: Fifty-four children and adolescents with diabetes mellitus (DM) and 98 children and adolescents without DM (Non-DM) wer...

hrp0095lb3 | Late Breaking | ESPE2022

High Glycated Hemoglobin instead of High Body Mass Index Might Increase the Urine N-acetyl-β-D-glucosaminidase Concentration in Children and Adolescents with Diabetes Mellitus

Jin Park Su , Bae Ahn Moon , Suh Jin-Soon , Soon Cho Kyoung , Ho Jung Min , Suh Byung-Kyu

Children with diabetes, and particularly those with obesity, have poor glycemic control. They are thus at higher risk of early microvascular complications. Renal tubulointerstitial markers are integral to evaluating diabetic nephropathy. Various biomarkers have been proposed, but their role in the obese pediatric population is uncertain. We investigated renal injury markers in children with diabetes, according to obesity, and determined their role as early predictors of diabet...

hrp0095p2-241 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Primary polydipsia in a male adolescent

Jeong Jang Min , Ju Choi Young , Shin Jungwoo , Bae Ahn Moon , Ho Jung Min , Suh Byung-Kyu

Introduction: Primary polydipsia is rare during adolescence and is known to be associated with psychiatric disorders or psychological stress. Differential diagnosis includes endocrine, neurologic, renal, and iatrogenic causes.Case Report: A 14-year-old male presented with polydipsia and polyuria that persisted for 6 years. His fluid intake was about 9 liters a day and he woke up for voiding once or two times every night....

hrp0086p1-p135 | Bone &amp; Mineral Metabolism P1 | ESPE2016

Low Bone Mineral Density in Adolescents with Leukemia After Hematopoietic Stem Cell Transplantation

Kyoung Cho Won , Bae Ahn Moon , Hee Kim Shin , Soon Cho Kyoung , Hyun Park So , Ho Jung Min , Suh Byung-Kyu

Background: Hematopoietic stem cell transplantation (HSCT) has improved the prognosis of children with malignant hematologic disease. However, it has had significant adverse effects on the endocrine system, including bone health. Limited studies are available to assess osteoporosis in survivors of adolescents after HSCT.Objective and hypotheses: We investigate the bone mineral density (BMD) and endocrinopathy/treatment factors associated with low BMD in ...

hrp0094p1-52 | Bone B | ESPE2021

Impact of Vertebral Fracture on Auxological Profile and Insulin-like Growth Factors of Children after Acute Lymphoblastic Leukemia Treatment

Bae Ahn Moon , Kim Sung Eun , Lee Na Yeong , Ki Kim Seul , Hee Kim Shin , Kyoung Cho Won , Soon Cho Kyoung , Ho Jung Min , Suh Byung-Kyu ,

Purpose: To investigate the overall prevalence of vertebral fractures (VF) following childhood acute lymphoblastic leukemia (ALL) treatment and examine the association of VF with growth trajectory and insulin-like growth factorsMethods: Children (n = 172; 59.3 % male) diagnosed with ALL at age between 2 and 18 years were assessed for VF by screening the lateral thoracolumbar spine radiographs (GenantÂ’s semi-quantitative met...