hrp0089p2-p059 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Arthrogryposis Multiplex Congenita Type II and Panhypopituitarism

Bideci Aysun , Doğer Esra , Kılınc Uğurlu Aylin , Demet Akbaş Emine , Camurdan Orhun , Cinaz Peyami

Aim: Arthrogryposis Multiplex Congenita type II is an autosomal dominant disease, characterized by multiple congenital contractures in the limbs without a primary neurological deficit. The most frequently observed clinical features are triangular face, palpebral fissures facing downwards, clarity in nasolabial folds, small mouth, high palate, adherent ear lobes, short stature, camptodactyly, ulnar deviations in the fingers, vertical talus and/or talipes equinovarus.<p clas...

hrp0089p3-p042 | Bone, Growth Plate &amp; Mineral Metabolism P3 | ESPE2018


Doğer Esra , Bideci Aysun , Boyunağa Oznur , Kılınc Uğurlu Aylin , Demet Akbaş Emine , Camurdan Orhun , Cinaz Peyami

Aim: Pseudoacondroplasia is a short extremity dwarfism characterized by lifelong arthralgia and early onset osteoarthritis. At birth there is a normal height and face appearance. At the beginning of walking, first symptom is a swaying walking nature. Typically, at second year of life, short height becomes apparent and leads to a disproportionate short-limb appearance. In childhood, joint pain in the broad joints especially in the lower extremities is common. Degenerative joint...

hrp0089p2-p101 | Diabetes &amp; Insulin P2 | ESPE2018

The Levels of Blood Glucose and Counting of Carbohydrate-Fat-Protein in Diabetic Children Using Pump with Aspart and Glulisine

Doğer Esra , Bozbulut Rukiye , Ercan Şebnem , Kılınc Uğurlu Aylin , Demet Akbaş Emine , Bideci Aysun , Camurdan Orhun , Cinaz Peyami

Introduction: In children with Type 1 diabetes, the insulin dose administered to, fasting blood sugar, the amount of food,contents and glycemic index can affect the postprandial blood sugar. Despite the intensive insulin therapy and carbohydrate (CHO) counting the expected improvements in glycemic control is not observed. Compared to other fast affecting analogues, Insulin glulisine has a faster onset of effect and a shorter duration. It has previously been reported that, in c...

hrp0089p3-p091 | Diabetes &amp; Insulin P3 | ESPE2018

Clinical and Epidemiological Features of Children with Type 1 Diabetes

Demir Şule , Cinaz Peyami , Doğer Esra , Kılınc Uğurlu Aylin , Demet Akbaş Emine , Bideci Aysun , Camurdan Orhun

Introduction: The world health organization has adopted diabetes as the most important health problem because of its increasing frequency and complications. Determination of changes in patient profile over the years due to type 1 diabetes (T1DM), the most common type of diabetes in childhood, is an important point in the follow up observation and treatment of diabetes.Aim: To determine the epidemiological and clinical characteristics of children and adol...

hrp0089p3-p366 | Thyroid P3 | ESPE2018

Clinical Features in Childhood Graves’ Disease

Kılınc Uğurlu Aylin , Doğer Esra , Demet Akbaş Emine , Bideci Aysun , Camurdan Orhun , Cinaz Peyami

Introduction: Hyperthyroidism is a disorder of the thyroid function in childhood that causes symptoms such as low school performance, headache, hyperactivity, palpitation, systolic hypertension, heat intolerance, diarrhea, weight loss inspite of tremendous appetite and tremor. Hyperthyroidism is very rare in childhood. Graves’ disease is responsible for 84% of pediatric cases and is the most common cause.Method: The demographic characteristics, refe...

hrp0089p2-p300 | Multisystem Endocrine Disorders P2 | ESPE2018

Somatostatin Experiment in Prohormone Convertase Deficiency

Eğritaş Odul , Uğurlu Aylin Kılınc , Doğer Esra , Demet Akbaş Emine , Bideci Aysun , Dalgıc Buket , Camurdan Orhun , Cinaz Peyami

Introduction: Prohormone convertase (PC) is a calcium-dependent serine endoprotease. PC 1/3 is responsible for converting hormones and neuropeptitids which has role on energy homeostasis, food intake,glucose metabolism (a-MSH, CART, NPY, AgRP, Orexin, Hypocretin, Ghrelin, insulin, cholecystokinin, GLP-1, GHRH, GnRH, ACTH, TRH) from proforms to active form. PC 1/3 deficiency’s clinical signs are diarrhea that started in the newborn period, obesity, hypoglycemia, multiple ...