hrp0086p2-p154 | Bone & Mineral Metabolism P2 | ESPE2016

Comparison of Two Different Stoss Therapy Doses in Children with Vitamin D Deficiency or Insufficiency without Rickets

Kocyigit Cemil , Catli Gonul , Ince Gulberat , Can Penbe S. , Dundar Bumin N

Background: There is no agreement on the optimal treatment of children with vitamin D deficiency or insufficiency without obvious signs of rickets.Objective and hypotheses: To compare the efficacy and side effects of two different stoss therapy regimens (10 000 IU/kg and 300 000 IU vitamin D3) in children with vitamin D deficiency or insufficiency without rickets.Method: A total of ...

hrp0086p1-p253 | Diabetes P1 | ESPE2016

Sulphonylurea Treatment in a Patient with Intermediate DEND Syndrome

Catli Gonul , Kocyigit Cemil , Gencpinar Pinar , Can Penbe S. , Dundar Nihal O. , Dundar Bumin N.

Background: DEND syndrome is characterized by developmental delay, epilepsy, and neonatal diabetes mellitus (NDM) due to mutations in KCNJ11 and ABCC8 genes. Intermediate DEND (iDEND) syndrome is a rare mild form with mild motor, speech or cognitive delay and an absence of epilepsy. Improvement in glycemic control and neurologic symptoms has been reported in three cases with iDEND syndrome.Objective and hypotheses: To present the result...

hrp0086p1-p481 | Fat Metabolism and Obesity P1 | ESPE2016

The Relation of Glycaemic Variability Obtained by Continuous Subcutaneous Glucose Monitoring with IL-6 and Adiponectin Levels in Obese Children with Metabolic Syndrome and Insulin Resistance

Kaya Abdurrahman , Kocyigit Cemil , Catli Gonul , Can Penbe S. , Sutcu Recep , Dundar Bumin N.

Background: Increased glycaemic variability (GV) (short-term fluctuations in blood glucose level) is associated with increased oxidative stress, vascular complications and mortality in diabetic and prediabetic patients.Objective and hypotheses: To investigate the relationship between GV and inflammatory markers in obese children with metabolic syndrome (MS) and insulin resistance (IR).Method: Fifty obese adolescents with insulin re...

hrp0086p2-p503 | Fat Metabolism and Obesity P2 | ESPE2016

The relationship between Subclinical Hypothyroidism and Iodine Deficiency, Serum Leptin Levels and Metabolic Syndrome in Obese Children

Dundar Bumin N. , Tanrısever Ozgur , Catli Gonul , Kocyigit Cemil , Can Penbe S. , Pirgon Ozgur

Background: Subclinical hypothyroidism (SH) has an incidence of 3.2–22.2% in obese children. The etiology of increased prevalence of SH is still unclear in obese individuals.Objective and hypotheses: To investigate the relation of SH with iodine deficiency, serum leptin levels and metabolic parameters in obese children and adolescents.Method: One hundred and fifty nine obese and 54 healthy children and adolescents were include...